The Application of Near Infrared Spectroscopy (NIRS) in the Detection of Lower Limb Compartment Syndrome

Launched by UNIVERSITY HOSPITAL BIRMINGHAM NHS FOUNDATION TRUST · Jun 15, 2009

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Eligibility criteria

• Inclusion Criteria:
• * Patients with one or more of the following injuries:
• • tibial fracture
• • crush injury/soft tissue injury to lower limb without fracture
• • pelvic fracture
• • major vascular injury below the aortic bifurcation
• • 2 or more long bone fractures
• • Any patient sustaining a traumatic injury with a base deficit ≥ 6 mEq/L within 12 hours of Hospital admission.
• • Any patient receiving ≥ 6 units packed red blood cells within 12 hours of hospital admission.
• Exclusion Criteria:
• • Age ≤ 16 years are excluded by design, as all pediatric cases are managed at Birmingham Childrens Hospital. There is no upper age limit.
• • Bilateral lower limb amputees.
• • Individuals who have received methylene blue within the previous week or during the study period.
• • Patient refusal to participated in the trial.
• • In the case of incapacitated patients, refusal by the patient's relatives/representatives, or where no representative can be identified.