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Search / Trial NCT00935090

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Launched by BARBARA ANN KARMANOS CANCER INSTITUTE · Jul 7, 2009

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Unspecified Adult Solid Tumor, Protocol Specific Accelerated Phase Chronic Myelogenous Leukemia Acute Undifferentiated Leukemia Adult Acute Lymphoblastic Leukemia In Remission Adult Acute Myeloid Leukemia In Remission Adult Acute Myeloid Leukemia With 11q23 (Mll) Abnormalities Adult Acute Myeloid Leukemia With Inv(16)(P13;Q22) Adult Acute Myeloid Leukemia With T(15;17)(Q22;Q12) Adult Acute Myeloid Leukemia With T(16;16)(P13;Q22) Adult Acute Myeloid Leukemia With T(8;21)(Q22;Q22) Atypical Chronic Myeloid Leukemia, Bcr Abl Negative Blastic Phase Chronic Myelogenous Leukemia Chronic Myelomonocytic Leukemia Chronic Phase Chronic Myelogenous Leukemia Mast Cell Leukemia Meningeal Chronic Myelogenous Leukemia Progressive Hairy Cell Leukemia, Initial Treatment Prolymphocytic Leukemia Recurrent Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Myeloid Leukemia Recurrent Adult T Cell Leukemia/Lymphoma Refractory Chronic Lymphocytic Leukemia Refractory Hairy Cell Leukemia Relapsing Chronic Myelogenous Leukemia Secondary Acute Myeloid Leukemia Stage I Adult T Cell Leukemia/Lymphoma Stage I Chronic Lymphocytic Leukemia Stage Ii Adult T Cell Leukemia/Lymphoma Stage Ii Chronic Lymphocytic Leukemia Stage Iii Adult T Cell Leukemia/Lymphoma Stage Iii Chronic Lymphocytic Leukemia Stage Iv Adult T Cell Leukemia/Lymphoma Stage Iv Chronic Lymphocytic Leukemia T Cell Large Granular Lymphocyte Leukemia Untreated Adult Acute Lymphoblastic Leukemia Untreated Adult Acute Myeloid Leukemia Untreated Hairy Cell Leukemia Recurrent Adult Hodgkin Lymphoma Stage I Adult Hodgkin Lymphoma Stage Ii Adult Hodgkin Lymphoma Stage Iii Adult Hodgkin Lymphoma Stage Iv Adult Hodgkin Lymphoma Anaplastic Large Cell Lymphoma Angioimmunoblastic T Cell Lymphoma Cutaneous B Cell Non Hodgkin Lymphoma Recurrent Cutaneous T Cell Non Hodgkin Lymphoma Stage I Cutaneous T Cell Non Hodgkin Lymphoma Stage Ii Cutaneous T Cell Non Hodgkin Lymphoma Stage Iii Cutaneous T Cell Non Hodgkin Lymphoma Stage Iv Cutaneous T Cell Non Hodgkin Lymphoma Recurrent Mycosis Fungoides/Sezary Syndrome Stage I Mycosis Fungoides/Sezary Syndrome Stage Ii Mycosis Fungoides/Sezary Syndrome Stage Iii Mycosis Fungoides/Sezary Syndrome Stage Iv Mycosis Fungoides/Sezary Syndrome Adult Grade Iii Lymphomatoid Granulomatosis Adult Nasal Type Extranodal Nk/T Cell Lymphoma Waldenstrom Macroglobulinemia Extranodal Marginal Zone B Cell Lymphoma Of Mucosa Associated Lymphoid Tissue Nodal Marginal Zone B Cell Lymphoma Splenic Marginal Zone Lymphoma Contiguous Stage Ii Adult Burkitt Lymphoma Contiguous Stage Ii Adult Diffuse Large Cell Lymphoma Contiguous Stage Ii Adult Diffuse Mixed Cell Lymphoma Contiguous Stage Ii Adult Diffuse Small Cleaved Cell Lymphoma Contiguous Stage Ii Adult Immunoblastic Large Cell Lymphoma Contiguous Stage Ii Adult Lymphoblastic Lymphoma Contiguous Stage Ii Grade 1 Follicular Lymphoma Contiguous Stage Ii Grade 2 Follicular Lymphoma Contiguous Stage Ii Grade 3 Follicular Lymphoma Contiguous Stage Ii Mantle Cell Lymphoma Contiguous Stage Ii Marginal Zone Lymphoma Contiguous Stage Ii Small Lymphocytic Lymphoma Stage I Adult Burkitt Lymphoma Stage I Adult Diffuse Large Cell Lymphoma Stage I Adult Diffuse Mixed Cell Lymphoma Stage I Adult Diffuse Small Cleaved Cell Lymphoma Stage I Adult Immunoblastic Large Cell Lymphoma Stage I Adult Lymphoblastic Lymphoma Stage I Grade 1 Follicular Lymphoma Stage I Grade 2 Follicular Lymphoma Stage I Grade 3 Follicular Lymphoma Stage I Mantle Cell Lymphoma Stage I Marginal Zone Lymphoma Stage I Small Lymphocytic Lymphoma Noncontiguous Stage Ii Adult Burkitt Lymphoma Noncontiguous Stage Ii Adult Diffuse Large Cell Lymphoma Noncontiguous Stage Ii Adult Diffuse Mixed Cell Lymphoma Noncontiguous Stage Ii Adult Diffuse Small Cleaved Cell Lymphoma Noncontiguous Stage Ii Adult Immunoblastic Large Cell Lymphoma Noncontiguous Stage Ii Adult Lymphoblastic Lymphoma Noncontiguous Stage Ii Grade 1 Follicular Lymphoma Noncontiguous Stage Ii Grade 2 Follicular Lymphoma Noncontiguous Stage Ii Grade 3 Follicular Lymphoma Noncontiguous Stage Ii Mantle Cell Lymphoma Noncontiguous Stage Ii Marginal Zone Lymphoma Noncontiguous Stage Ii Small Lymphocytic Lymphoma Stage Iii Adult Burkitt Lymphoma Stage Iii Adult Diffuse Large Cell Lymphoma Stage Iii Adult Diffuse Mixed Cell Lymphoma Stage Iii Adult Diffuse Small Cleaved Cell Lymphoma Stage Iii Adult Immunoblastic Large Cell Lymphoma Stage Iii Adult Lymphoblastic Lymphoma Stage Iii Grade 1 Follicular Lymphoma Stage Iii Grade 2 Follicular Lymphoma Stage Iii Grade 3 Follicular Lymphoma Stage Iii Mantle Cell Lymphoma Stage Iii Marginal Zone Lymphoma Stage Iii Small Lymphocytic Lymphoma Stage Iv Adult Burkitt Lymphoma Stage Iv Adult Diffuse Large Cell Lymphoma Stage Iv Adult Diffuse Mixed Cell Lymphoma Stage Iv Adult Diffuse Small Cleaved Cell Lymphoma Stage Iv Adult Immunoblastic Large Cell Lymphoma Stage Iv Adult Lymphoblastic Lymphoma Stage Iv Grade 1 Follicular Lymphoma Stage Iv Grade 2 Follicular Lymphoma Stage Iv Grade 3 Follicular Lymphoma Stage Iv Mantle Cell Lymphoma Stage Iv Marginal Zone Lymphoma Stage Iv Small Lymphocytic Lymphoma Recurrent Adult Burkitt Lymphoma Recurrent Adult Diffuse Large Cell Lymphoma Recurrent Adult Diffuse Mixed Cell Lymphoma Recurrent Adult Diffuse Small Cleaved Cell Lymphoma Recurrent Adult Grade Iii Lymphomatoid Granulomatosis Recurrent Adult Immunoblastic Large Cell Lymphoma Recurrent Adult Lymphoblastic Lymphoma Recurrent Grade 1 Follicular Lymphoma Recurrent Grade 2 Follicular Lymphoma Recurrent Grade 3 Follicular Lymphoma Recurrent Mantle Cell Lymphoma Recurrent Marginal Zone Lymphoma Recurrent Small Lymphocytic Lymphoma Intraocular Lymphoma Primary Central Nervous System Non Hodgkin Lymphoma Primary Central Nervous System Hodgkin Lymphoma Post Transplant Lymphoproliferative Disorder Chronic Eosinophilic Leukemia Chronic Neutrophilic Leukemia Primary Myelofibrosis Essential Thrombocythemia Polycythemia Vera Extramedullary Plasmacytoma Isolated Plasmacytoma Of Bone Stage I Multiple Myeloma Stage Ii Multiple Myeloma Stage Iii Multiple Myeloma Primary Systemic Amyloidosis Refractory Multiple Myeloma De Novo Myelodysplastic Syndromes Previously Treated Myelodysplastic Syndromes Secondary Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable

ClinConnect Summary

This clinical trial is studying a special type of imaging called 3'-deoxy-3'-[18F] fluorothymidine (FLT) PET imaging in patients who have various types of cancer, including brain tumors, leukemia, lymphoma, and other blood cancers. The goal of this study is to see if this imaging can help doctors find and diagnose cancer more accurately. It may also help them understand how well a patient might respond to treatment and assist in planning the best treatment options.

To be eligible for this trial, participants need to have a confirmed cancer diagnosis or be awaiting a biopsy or surgery for a suspected cancer. They should be able to stay still during the imaging process. Patients who are pregnant or nursing cannot participate, and those who can become pregnant must use effective birth control during the study. If you join the trial, you can expect to undergo FLT PET imaging, which is a non-invasive procedure that helps gather important information about your cancer. The trial is currently recruiting participants, and all genders and adults aged 18 and older are welcome to apply.

Gender

ALL

Eligibility criteria

  • DISEASE CHARACTERISTICS:
  • * Meets one of the following criteria:
  • Histologically confirmed solid tumor or hematologic malignancy
  • Awaiting biopsy or surgery for cancer evaluation of a mass detected on exam or standard imaging
  • PATIENT CHARACTERISTICS:
  • Able to lie still in the PET scanner
  • Girth and weight must be suitable to enter the gantry
  • Not pregnant or nursing
  • Negative pregnancy test
  • Fertile patients must use effective contraception
  • PRIOR CONCURRENT THERAPY:
  • Not specified

About Barbara Ann Karmanos Cancer Institute

The Barbara Ann Karmanos Cancer Institute, a leading nonprofit cancer research and treatment center located in Detroit, Michigan, is dedicated to advancing innovative cancer therapies and improving patient outcomes through rigorous clinical trials. Affiliated with Wayne State University, the institute emphasizes a multidisciplinary approach, integrating cutting-edge research with compassionate patient care. With a commitment to translating laboratory discoveries into effective treatments, Karmanos plays a pivotal role in the national landscape of cancer research, focusing on personalized medicine and the development of novel therapeutic strategies to combat various forms of cancer.

Locations

Detroit, Michigan, United States

Patients applied

0 patients applied

Trial Officials

Anthony F. Shields, MD, PhD

Principal Investigator

Barbara Ann Karmanos Cancer Institute

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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