Vaginal Misoprostol for Cervical Ripening Prior to Endometrial Biopsy
Launched by UNIVERSITY OF SASKATCHEWAN · Aug 5, 2009
Trial Information
Current as of July 21, 2025
Withdrawn
Keywords
ClinConnect Summary
Endometrial biopsy is a common gynecological office procedure performed to assist in the pathological diagnosis of abnormal vaginal bleeding. The procedure can be painful and it may be difficult to obtain an endometrial sample with a hard and closed cervix. Giving Misoprostol before the procedure may soften the cervix sufficiently to allow an easier and more successful test. This medication has been tested before hysteroscopy and in some patients it has been shown to be beneficial.
104 patients need to be recruited for this study. Participants will be divided according to pre-menopausal an...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Patients with abnormal uterine bleeding
- • Age over 35 years
- Exclusion Criteria:
- • Pregnancy
- • Allergy to or contraindication to prostaglandin use
- • Active genital tract infections
- • Bleeding disorders
About University Of Saskatchewan
The University of Saskatchewan is a leading research institution dedicated to advancing health sciences through innovative clinical trials and studies. With a commitment to improving patient outcomes, the university leverages its interdisciplinary expertise and state-of-the-art facilities to conduct rigorous and ethically sound research. By fostering collaborations among researchers, healthcare professionals, and industry partners, the University of Saskatchewan aims to translate scientific discoveries into practical applications that enhance healthcare delivery and contribute to the well-being of communities both locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Saskatoon, Saskatchewan, Canada
Patients applied
Trial Officials
Roger Pierson, PhD
Study Chair
University of Saskatchewan, Dept. of Obstetrics and Gynecology, College of Medicine
Anita Harding, MBChB
Principal Investigator
University of Saskatchewan, Dept. of Obstetrics and Gynecology, College of Medicine
Thirza Smith, MD, FRCS
Principal Investigator
University of Saskatchewan, Dept. of Obstetrics and Gynecology
Marilyn Davidson, FRCSC
Principal Investigator
University of Saskatchewan, Dept. of Obstetrics and Gynecology
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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