A Study of the Pharmacokinetics of Two Formulations of MK-1006 (MK-1006-010 AM1)(COMPLETED)

Launched by MERCK SHARP & DOHME LLC · Sep 17, 2009

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Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • is a male or a female of non-child bearing potential
• • has type 2 diabetes (T2D) and is either being treated with diet and exercise alone or with a single or combination oral anti-hyperglycemic agent(s)
• • has been a nonsmoker for at least 6 months
• Exclusion Criteria:
• • has a history of stroke, chronic seizures, or major neurological disorder
• • has a history of major endocrine (except T2D), gastrointestinal, cardiovascular, blood, liver, immune, kidney, respiratory, or genitourinary abnormalities or diseases
• • has a history of cancer, except certain skin or cervical cancers or cancer that was successfully treated more than 10 years prior to screening
• • has unstable or rapidly progressing diabetic retinopathy and/or neuropathy
• • has had an eye infection or other inflammation of the eye in the 2 weeks prior to screening
• • has glaucoma or is blind
• • has had incisional eye surgery in the last 6 months or laser eye surgery in the last 3 months (Lasik is permitted)
• • has a history of type 1 diabetes
• • has symptomatic coronary artery disease
• • consumes excessive amounts of alcohol and/or caffeine