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Search / Trial NCT00991276

Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And Associated Sleep Disturbance

Launched by PFIZER'S UPJOHN HAS MERGED WITH MYLAN TO FORM VIATRIS INC. · Oct 6, 2009

Trial Information

Current as of June 25, 2025

Completed

Keywords

Restless Legs Syndrome Rls Polysomnography Psg Sleep Disturbance Patient Reported Outcome

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Diagnosis of restless legs syndrome with a total score of 15 or more points on the International RLS rating scale (IRLS).
  • RLS symptoms interfering with sleep on 3 or more nights per week for at least 6 months.
  • PSG confirmation of WASO of at least 60 min, PLMI of 10 or more, and total sleep time of at least 3 hrs and less than 6.5 hrs.
  • Exclusion Criteria:
  • Secondary RLS.
  • Daytime RLS symptoms requiring treatment.
  • Primary sleep disorder.
  • Sleep apnea.
  • Night or shift work.
  • Concurrent medical disorder that could interfere with efficacy assessment or present a safety concern.
  • Pregnant or lactating women.
  • Women of child-bearing potential not using acceptable method of birth control.
  • Use of prohibited medication.

About Pfizer's Upjohn Has Merged With Mylan To Form Viatris Inc.

Viatris Inc. is a global healthcare company formed from the merger of Pfizer's Upjohn division and Mylan, dedicated to providing access to high-quality medicines, including generics and specialty pharmaceuticals. With a strong commitment to innovation and patient-centric solutions, Viatris leverages a diverse portfolio and extensive global reach to address the evolving healthcare needs of patients worldwide. The company aims to create sustainable healthcare solutions by combining expertise in pharmaceutical development, manufacturing, and distribution, ultimately enhancing patient outcomes and improving overall health systems.

Locations

Santa Monica, California, United States

Atlanta, Georgia, United States

Crestview Hills, Kentucky, United States

Winston Salem, North Carolina, United States

Little Rock, Arkansas, United States

Tucson, Arizona, United States

Aurora, Colorado, United States

Raleigh, North Carolina, United States

Austin, Texas, United States

Dallas, Texas, United States

San Diego, California, United States

Phoenix, Arizona, United States

Redlands, California, United States

Macon, Georgia, United States

Oklahoma City, Oklahoma, United States

Chevy Chase, Maryland, United States

Columbia, South Carolina, United States

Baton Rouge, Louisiana, United States

Santa Ana, California, United States

Spring Hill, Florida, United States

Hallandale Beach, Florida, United States

Portage, Michigan, United States

Hickory, North Carolina, United States

Overland Park, Kansas, United States

Miami, Florida, United States

Cincinnati, Ohio, United States

Kalamazoo, Michigan, United States

Middleburg Heights, Ohio, United States

New York, New York, United States

Pembroke Pines, Florida, United States

Brighton, Massachusetts, United States

Pasadena, California, United States

Lexington, Kentucky, United States

Clarks Summit, Pennsylvania, United States

Jasper, Alabama, United States

Lafayette Hill, Pennsylvania, United States

Burlingame, California, United States

Dublin, Ohio, United States

Patients applied

0 patients applied

Trial Officials

Pfizer CT.gov Call Center

Study Director

Pfizer

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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