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Search / Trial NCT00993252

Canadian Computed Tomography (CT) Head Rule Study

Launched by OTTAWA HOSPITAL RESEARCH INSTITUTE · Oct 9, 2009

Trial Information

Current as of May 21, 2025

Completed

Keywords

Head Injury Radiography Clinical Impact Dissemination

ClinConnect Summary

Background: Each year, Canadian emergency department physicians treat 600,000 patients with head injury. Many of these are adults with "minor head injury", i.e. loss of consciousness or amnesia and a Glasgow Coma Scale (GCS) score of 13-15. Only 6.2% of these "minor" patients have some acute injury on computed tomography (CT scan) and only 0.5% have an epidural hematoma requiring surgery. Among Canadian teaching hospital emergency departments, we have shown a fourfold variation in use of CT and that a small but important number of intracranial hematomas are missed at the first visit. This r...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Consecutive adult patients presenting to one of the study hospital EDs after sustaining acute minor head injury will be enrolled into the study. Eligibility as an 'acute minor head injury' case will be determined by the patient having all of the following characteristics upon arrival in the ED.
  • 1. Blunt trauma to the head resulting in witnessed loss of consciousness, definite amnesia, or witnessed disorientation, no matter how brief; this may be determined from the patient or from the report of a witness (the patient will be asked specific questions: 'do you remember the accident?', 'how did you get to the hospital?', 'have you talked to me before?').
  • 2. Initial ED GCS score of 13 or greater as ascertained by the attending physician (e.g. opens eyes spontaneously, obeys commands, but speech may include only comprehensible but inappropriate words).
  • 3. Injury within the past 24 hours.
  • Exclusion Criteria:
  • 1. less than 16 years,
  • 2. 'minimal' head injury i.e. no loss of consciousness, amnesia, or disorientation,
  • 3. no clear history of trauma as the primary event (for example primary seizure or syncope),
  • 4. GCS score of less than 13,
  • 5. head injury occurred more than 24 hours previously,
  • 6. obvious penetrating skull injury or depressed fracture,
  • 7. acute focal neurological deficit (motor or cranial nerve) that cannot be ascribed to an extracerebral cause, for example, traumatic mydriasis or peripheral neuropathy,
  • 8. have suffered a seizure prior to assessment in the ED,
  • 9. a bleeding disorder or current use of oral anticoagulants,125 or
  • 10. returned for reassessment of the same head injury

About Ottawa Hospital Research Institute

The Ottawa Hospital Research Institute (OHRI) is a leading academic research institute dedicated to advancing health and healthcare through innovative research and evidence-based practices. Affiliated with The Ottawa Hospital and the University of Ottawa, OHRI fosters a collaborative environment that brings together clinicians, scientists, and trainees to conduct groundbreaking clinical trials and translational research. With a focus on improving patient outcomes, OHRI specializes in a wide range of fields, including cancer, cardiovascular health, and regenerative medicine. The institute is committed to ethical research practices and the dissemination of knowledge to enhance public health and inform healthcare policy.

Locations

Kingston, Ontario, Canada

London, Ontario, Canada

Vancouver, British Columbia, Canada

Edmonton, Alberta, Canada

Ottawa, Ontario, Canada

Ottawa, Ontario, Canada

Westminster, British Columbia, Canada

Elgin, Ontario, Canada

Toronto, Ontario, Canada

Toronto, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Ian G Stiell, MD MSc

Principal Investigator

University of Ottawa

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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