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Search / Trial NCT01018355

The Effect of Device Closure of Patent Foramen Ovale in Elderly Patients With Crytogenic Stoke/TCI

Launched by HILLEROD HOSPITAL, DENMARK · Nov 20, 2009

Trial Information

Current as of July 22, 2025

Terminated

Keywords

Patent Foramen Ovale Pfo Stroke Tia Percutaneus Closure Intervention

ClinConnect Summary

Prior to birth the fetal heart has a connection between the two atrias of the heart. After labour this connection often closes. About 10-15 % these connections remains open. This phenomenon is called patent foramen ovale or PFO, and is in most cases unsymptomatic.

The prevalence of PFO in patients with crytogenic (without known causes) stroke is much higher (about 40%)than the general population (about 10%). This has led to the theory that the presence of PFO can lead to stroke, by the passage of emboli from the peripheral venous circulation through the PFO to the brain by right-to-left sh...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Stroke or TIA within 30 days
  • Above 50 years of age
  • Exclusion Criteria:
  • Deceases og the esophagus
  • Dementia
  • Allergy to aspirin
  • Risk of non-compliance
  • Lacking ability to give written or oral consent
  • Atrial Fibrillation
  • Neurological deficit lasting less than 6 hours

About Hillerod Hospital, Denmark

Hillerød Hospital, located in Denmark, is a leading healthcare institution dedicated to advancing medical science through innovative clinical research. As a prominent sponsor of clinical trials, the hospital is committed to improving patient outcomes and healthcare practices by rigorously evaluating new treatments and interventions. With a multidisciplinary team of experienced researchers and healthcare professionals, Hillerød Hospital fosters a collaborative environment that prioritizes patient safety, ethical standards, and scientific integrity. The institution plays a vital role in contributing to the global medical community by facilitating high-quality research across various therapeutic areas.

Locations

Hillerød, Region H, Denmark

Patients applied

0 patients applied

Trial Officials

Christian S Hansen, dr.

Principal Investigator

Hillerød Hospital. dept. of cardiology and endocrinology

Niels Tønder, Dr.

Study Director

Hillerød Hospital. dept. of cardiology and endocrinology

Kasper K Iversen, Dr.

Study Director

Hillerød Hospital. dept. of cardiology and endocrinology

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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