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Search / Trial NCT01087333

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

Launched by NATIONAL CANCER INSTITUTE (NCI) · Mar 13, 2010

Trial Information

Current as of June 28, 2025

Recruiting

Keywords

Cytotoxicity Assay Neutralizing Antibodies Apheresis Flow Cytometry Hemolytic Uremic Syndrome (Hus) Natural History

ClinConnect Summary

This clinical trial is focused on studying hairy cell leukemia and other types of blood cancers, like chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Researchers want to collect samples such as blood, urine, and tissue from patients with these cancers, as well as from healthy volunteers. These samples will help scientists learn more about these diseases and work on developing new treatments using a special type of drug called immunotoxins, which can target and kill cancer cells.

To participate, you need to be at least 18 years old and either have been diagnosed with a blood cancer or be a healthy volunteer with no history of such diseases. If you are a patient, you will be asked to provide various samples as needed, while healthy volunteers will only need to provide blood and urine samples. It’s important to note that this trial is not providing any treatment; it's purely for research purposes. Additionally, if you are pregnant, you won't be eligible to participate. This study is currently recruiting participants, and your involvement could help advance cancer research significantly.

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • All participants
  • 18 years of age and older
  • Desire of the individual to submit data and samples for research
  • Ability to understand and the willingness to sign a written informed consent document.
  • Individuals with cancer
  • -Participants may have a diagnosis of hematologic malignancy or solid tumor. These participants would not be excluded if they were in long-term complete remission.
  • Normal donors (Individuals without cancer)
  • -Individuals must not have a current or prior diagnosis of a hematologic malignancy or solid tumor.
  • EXCLUSION CRITERIA:
  • All participants
  • -Known pregnancy at enrollment. NOTE: A pregnancy test will be required in individuals on study prior to any procedure done for research purposes that is greater than minimal risk.

About National Cancer Institute (Nci)

The National Cancer Institute (NCI) is a prominent component of the National Institutes of Health (NIH), dedicated to advancing cancer research and improving patient outcomes through innovative clinical trials. As a leading sponsor of cancer-related studies, NCI focuses on facilitating the development of new therapies, enhancing prevention strategies, and understanding the biology of cancer. The institute collaborates with academic institutions, healthcare providers, and industry partners to conduct rigorous clinical trials that aim to translate scientific discoveries into effective treatments. NCI’s commitment to fostering a robust research environment supports the mission to eliminate cancer as a major health problem.

Locations

Bethesda, Maryland, United States

Bethesda, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Robert J Kreitman, M.D.

Principal Investigator

National Cancer Institute (NCI)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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