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Search / Trial NCT01097889

Evaluating the Relative Effectiveness of Two Feeding Interventions for the Treatment of Moderate Acute Malnutrition

Launched by THE HOSPITAL FOR SICK CHILDREN · Mar 31, 2010

Trial Information

Current as of July 22, 2025

Completed

Keywords

United Nations World Food Programme Blended Food (Csb) Ready To Use Supplementary Foods (Rusf) Plumpy®

ClinConnect Summary

This research protocol will be embedded as a component of the UN World Food Programme (WFP) -supported Supplementary Feeding programmes in Ethiopia. The proposed study is a prospective cluster-randomized equivalence trial that will compare the relative effectiveness of two feeding interventions in four woredas (districts). Research will be implemented in two comparable woredas (one with CSB and one with RUSF), in two different areas in Sidama zone that represent different livelihood zones, main source of crop income, and level of food insecurity

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All children 6 to 60 months of age who are identified as malnourished based on MUAC measurements with WFH ≥70 to \<80%.
  • Exclusion Criteria:
  • Children with WFH \< 70% or presenting with bilateral pitting oedema (they will be referred to therapeutic feeding programme).
  • Children with any illness or clinical condition that prevents them from safely ingesting either supplementary foods. A child is medically assessed upon admission for any complicated clinical condition (oedema, malaria, vomiting, chronic diarrhea, infections, appetite, etc) that would require medical care and those children will be referred to the therapeutic feeding programme.
  • All children transferred from the therapeutic feeding programme directly into the supplementary feeding programme - however they will not be included in the research study.
  • Children with WFH \> 80% but MUAC 110 to 120 mm- they will be admitted to SFP however will not be included in the research study.

About The Hospital For Sick Children

The Hospital for Sick Children (SickKids) is a leading pediatric health care and research institution located in Toronto, Canada. With a commitment to advancing child health through innovative research, education, and clinical care, SickKids is recognized globally for its expertise in pediatric medicine. The hospital actively sponsors clinical trials aimed at improving treatment outcomes and enhancing the quality of life for children with various health conditions. By fostering collaboration among multidisciplinary teams and leveraging state-of-the-art facilities, SickKids strives to translate research findings into tangible advancements in pediatric care, ensuring that children receive the best possible treatments based on the latest scientific evidence.

Locations

Toronto, Ontario, Canada

Sidama Zone, Southern Ethiopia, Ethiopia

Patients applied

0 patients applied

Trial Officials

Stanley Zlotkin, MD

Principal Investigator

The Hospital for Sick Children

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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