The Effect of Lactisole on the Responses to Glucose Solution
Launched by NORTHERN CARE ALLIANCE NHS FOUNDATION TRUST · May 10, 2010
Trial Information
Current as of June 27, 2025
Unknown status
Keywords
ClinConnect Summary
Obesity is epidemically prevalent and a major risk factor for chronic diseases making it fundamental to understand the pathways controlling food intake. During the course of a meal and afterwards the gut and brain communicate to control how full the eater feels and thus control the amount of food eaten. The information relayed from the gut to the brain regarding ingested nutrients is of increasing importance and understanding the mechanisms by which nutrient molecules are initially detected in the gut and how they signal to the brain to influence food intake is critical to the development o...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Aged between 18-45 years
- • BMI between 18-25kg/m2
- • General good health
- Exclusion Criteria:
- • Underweight or Overweight (Body Mass Index \<19 or \>25 kg.m-2)
- • Females who are pregnant or breastfeeding
- • Currently taking medication (except females taking oral contraceptive)
- • Smokers
- • Currently dieting or have experienced a weight change +/- 3kg in past 6 months
- • Metabolic disorders (eg. Type 2 diabetes)
- • History of gastrointestinal disorders
- • Participation in other research in past 3 months
About Northern Care Alliance Nhs Foundation Trust
The Northern Care Alliance NHS Foundation Trust is a leading healthcare organization in the UK, dedicated to providing high-quality patient care and advancing medical research. Formed through the collaboration of several NHS hospitals and community services, the Trust is committed to innovation and excellence in clinical practice. Its extensive clinical trial portfolio encompasses a wide range of therapeutic areas, aiming to enhance patient outcomes and contribute to the global body of medical knowledge. By fostering partnerships with academic institutions and industry leaders, the Northern Care Alliance NHS Foundation Trust plays a pivotal role in translating research findings into effective treatments and improved healthcare delivery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Manchester, , United Kingdom
Patients applied
Trial Officials
David Thompson, FRCP, fMedSci,
Principal Investigator
University of Manchester
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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