Mean Reticulated Haemoglobin (Hb) Content (RetHe) Analysis of Renal Patients

Launched by UNIVERSITY OF ULSTER · May 19, 2010

Keywords

ClinConnect Summary

Reference Range Testing for new test RET-He will be performed on excess blood available on randomly selected anonamised samples obtained from the daily workload of the laboratory once all the clinically requested analysis has been completed.

100 samples (50 men / 50 women)determined to have normal parameters(as defined by Dacie et al, 10th Edition) and 100 samples (50 men / 50 women)determined to be iron deficient (as defined by Dacie et al, 10th Edition)will be processed for new test parameter (RetHe) under a coded number to ensure no identifying data is recorded. The samples will be arch...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Two groups of random routine anonamised blood samples (for use in determinimg a local normal range for the Reticulated Haemoglobin Content \[RetHe\])will be included in the study:
• • Normal red blood cell (RBC) Indices (Hb , Haematocrit, Mean Cell Volume ande Mean Cell Haemoglobin Content) ; an attempt will be made to select an equal mixture of men / women and an appropriate age spread to provide a valid control range for the group of test subjects (renal patients) The student Investigator will ask Haematology staff to record minimum details of iron deficient patients and "normal" test results noted at routine validation \[positive identification number (barcode)/ age / sex\] - these samples will be coded and additionally analysed for RetHe test.
• Exclusion Criteria:
• • All renal patient who have had surgery and / or a Blood Transfusion OR bleeding episodes within the last month prior to the study are excluded as this would interfere with red cell parameters.
• • All patients \< 16 years and \>85 years are excluded from the study.