To Investigate the Safety and Tolerability of TC-5214 Following Oral Administration of Multiple Doses for up to 8 Days

Launched by ASTRAZENECA · Jun 15, 2010

Keywords

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Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male and nonpregnant, nonlactating female, with suitable veins for cannulation or repeated venipuncture
• • Contraceptive use from the first dose of investigational product until12 weeks after their last dose
• • Body mass index (BMI) between 19 and 32 kg/m2 and weigh at least 50 kg
• Exclusion Criteria:
• • History of any clinically significant medical, neurologic or psychiatric disease or disorder which, in the opinion of the Investigator and Sponsor, may either put the volunteer at risk because of participation in the study, or influence the results of
• • History of gastrointestinal surgery (except for cholecystectomy and appendectomy) or unintentional rapid weight loss
• • Volunteers with a history of suicide attempts in the past year and/or seen by the Investigator as having a significant history of risk of suicide or homicide, or considered at risk for suicide or homicide during the study