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Search / Trial NCT01148108

Study of Canfosfamide in Refractory or Relapsed Mantle Cell, Diffuse Large B Cell Lymphoma and Multiple Myeloma

Launched by TELIK · Jun 18, 2010

Trial Information

Current as of July 03, 2025

Completed

Keywords

Nhl Non Hodgkins Lymphoma Lymphoma Mantle Cell Diffuse Large B Cell Multiple Myeloma Telcyta Canfosfamide Tlk286 Prodrug Enzyme Activated Drug Glutathione Transferase P1 1 Activated Drug Gs Tp1 1 Activated Drug Glutathione Transferase Activated Drug Glutathione Glutathione Analong

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • relapsed or refractory disease
  • histologically or cytologically confirmed disease
  • characteristic immunophenotypic profiles
  • measurable disease (for lymphoma patients)
  • ECOG performance status of 0-2
  • adequate liver and kidney function
  • adequate bone marrow reserves
  • ineligible or unwilling to undergo autologous stem cell transplantation
  • Exclusion Criteria:
  • failure to recover from any major surgery within 4 weeks of study entry
  • pregnant or lactating women
  • women of child-bearing potential not using reliable and appropriate contraception
  • routine prophylactic use of G-CSF required within 2 weeks of study entry
  • Grade 3 or higher peripheral neuropathy
  • history of hepatitis B virus or HIV
  • central nervous system or meningeal involvement by lymphoma or multiple myeloma

About Telik

Telik, a biopharmaceutical company, focuses on the discovery and development of innovative therapies for cancer and other serious diseases. Leveraging its proprietary drug development platform, Telik aims to identify and advance novel compounds that target critical pathways in tumor biology. With a commitment to scientific excellence and patient-centric approaches, the company strives to bring transformative treatments to market, addressing unmet medical needs and improving the quality of life for patients worldwide. Through rigorous clinical trials and collaborations, Telik is dedicated to fostering advancements in therapeutic options and enhancing outcomes in oncology.

Locations

New Brunswick, New Jersey, United States

Patients applied

0 patients applied

Trial Officials

Joseph Bertino, MD

Principal Investigator

Rutgers Cancer Institute of New Jersey

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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