CIBMTR Research Database

Launched by CENTER FOR INTERNATIONAL BLOOD AND MARROW TRANSPLANT RESEARCH · Jul 19, 2010

Keywords

ClinConnect Summary

The CIBMTR Research Database is a study aimed at gathering valuable information about stem cell transplants and cellular therapies, which are treatments often used for various blood cancers, solid tumors, and other conditions. The main goal is to understand how these treatments work, how well patients recover from them, and how recovery can be improved. Researchers will also look into factors like the genetics of both donors and recipients to see how they might affect recovery. The study will help identify ways to improve access to these treatments for different groups of patients and understand how well donors feel after giving stem cells.

To participate in this research, individuals must either be recipients of a stem cell transplant (from a related or unrelated donor) or have experienced a marrow toxic injury and received treatment at a participating center. This includes adults and children, regardless of their ability to make medical decisions. Donors who have registered to provide stem cells for a patient are also eligible. Participants will have their medical information collected to help researchers learn more about these important therapies, and they can expect to be involved in a study that aims to enhance future treatments and patient care.

Gender

ALL

Eligibility criteria

• • Eligibility to Participate in the Research Database
• Recipient Eligibility Criteria:
• • Any recipient of an unrelated or related donor or autologous HSC transplant in a CIBMTR center is eligible to participate in the Research Database. This includes adults with and without decision making capacity, and children.
• Individual with Marrow Toxic Injury Eligibility Criteria:
• • Any individual who is treated for a marrow toxic injury at a center participating in the NMDP's Radiation Injury Transplant Network (RITN) is eligible to participate in the Research Database. This includes adults with and without decision making capacity, and children. Eligible individuals may have received supportive care only, growth factor support, HSC transplant or other appropriate medical treatment for marrow toxic injury. Treatments applied are at the discretion of the care facility, and are not determined by the NMDP or CIBMTR.
• Unrelated Donor Eligibility Criteria:
• • All donors registered on the NMDP Registry who have been requested to donate a product for a recipient are eligible to participate in the Research Database.
• • All maternal cord blood donors are enrolled in the NMDP Cord Blood Bank Investigational New Drug (IND) protocol, and sign an informed consent document specific to that protocol. Data collected as part of the Cord Blood Bank protocol are included in the Research Database.