Dydrogesterone Versus Intravaginal Progesterone in the Luteal Phase Support
Launched by UNIVERSITY OF ZAGREB · Aug 9, 2010
Trial Information
Current as of July 27, 2025
Completed
Keywords
ClinConnect Summary
The use of gonadotropin-releasing hormone (GnRH) agonists in the ovarian stimulation, which prevents a premature surge of luteal hormone (LH), ultimately leads to suppression of the pituitary gland and high levels of estrogen observed during induced cycles result in inhibiting effect on the implantation of human embryos.
The luteal support in in-vitro-fertilization (IVF) cycles can be prolonged using human chorion gonadotropin(hCG) and/or progesterone.
Since it has been noted that the use of hCG was related with higher risks of the onset of ovarian hyperstimulation syndrome (OHSS), proges...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • routine ovulation induction protocol with GnRH agonist
- • less than three prior IVF cycles
- • at least three aspirated oocytes
- • BMI \<35 kg/m2
- • age \<45 years
- Exclusion Criteria:
- • history of dysfunctional uterine bleeding
- • acute urogenital disease
- • recurrent miscarriage
- • previous allergic reactions to a progesterone products
About University Of Zagreb
The University of Zagreb, a leading academic institution in Croatia, is committed to advancing medical research and improving healthcare outcomes through innovative clinical trials. With a focus on interdisciplinary collaboration, the university harnesses its extensive expertise and state-of-the-art facilities to conduct rigorous clinical studies that address pressing health challenges. By fostering partnerships with healthcare professionals, industry leaders, and regulatory bodies, the University of Zagreb aims to translate scientific discoveries into practical applications, ultimately enhancing patient care and contributing to the global body of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Zagreb, , Croatia
Patients applied
Trial Officials
Jozo Tomic, M.D.
Principal Investigator
Department of Human Reproduction, University Hospital Center Sisters of Mercy
Vlatka Tomic, M.D.
Study Chair
Department of Human Reproduction, University Hospital Center Sisters of Mercy
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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