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Search / Trial NCT01181739

Computed Tomography (CT) Colonography Versus Optical Colonoscopy

Launched by UNIVERSITY OF BRITISH COLUMBIA · Aug 12, 2010

Trial Information

Current as of June 25, 2025

Unknown status

Keywords

Colonoscopy Virtual Colonoscopy Colonography Colorectal Cancer Colonic Polyps Screening

ClinConnect Summary

1. Purpose To study the Effect of Experience and Training on the Accuracy of CT (Computed Tomography) Colonography in Comparison with Optical Colonoscopy in the Detection of Colonic Neoplasia

2. Hypotheses

1. The accuracy (sensitivity and specificity) of interpretation of the CTC images will improve with each 100 scans examined. Less time will be required to interpret the CTC images after each successive 100 scans. The accuracy of each of the observers will be similar.
2. The sensitivity and specificity will be similar for CTC and OC for the last 100 patients undergoing both examinations....

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 19 - 65 years of age
  • Have a recognized indication for optical colonoscopy, including high risk for colorectal cancer
  • Over 45 years of age with a family history of colorectal cancer, those with positive screening tests (FOBT, DRE, flexible sigmoidoscopy and contrast enema)
  • Previous history of advanced adenomas and those with suggestive symptoms and signs (bleeding, abdominal pain, anemia)
  • Must be able to read and understand English and must be able to give informed consent

About University Of British Columbia

The University of British Columbia (UBC) is a leading research institution located in Vancouver, Canada, renowned for its commitment to advancing health sciences through innovative research and education. As a prominent clinical trial sponsor, UBC leverages its interdisciplinary expertise and state-of-the-art facilities to conduct rigorous clinical studies aimed at improving patient outcomes across various medical fields. The university fosters collaborations with healthcare professionals, industry partners, and community stakeholders to translate research findings into practical applications, thereby contributing to the global advancement of medicine and public health.

Locations

Vancouver, British Columbia, Canada

Vancouver, British Columbia, Canada

Patients applied

0 patients applied

Trial Officials

Robert Enns, Dr.

Principal Investigator

University of British Columbia

Jacquie Brown, Dr.

Study Director

University of British Columbia

Jennifer Telford, Dr.

Study Director

University of British Columbia

Gregory Rosenfeld, Dr.

Study Director

University of British Columbia

Pari Tiwari, Dr.

Study Director

University of British Columbia

Darin Krygier, Dr.

Study Director

University of British Columbia

Brian Bressler, Dr.

Study Director

University of British Columbia

Patrick Vos, Dr.

Study Director

University of British Columbia

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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