Telmisartan+Amlodipine Fixed Dose Combination in Hypertension

Launched by BOEHRINGER INGELHEIM · Sep 16, 2010

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • 1. Aged at least 18 years at the date of signing the consent form
• • 2. For treatment-naïve patients: hypertension defined by a mean seated diastolic blood pressure (DBP) equal or more than 100 mmHg measured by manual cuff sphygmomanometry at visit 1 and 2; For pretreatment patients: hypertension defined by a mean seated diastolic blood pressure equal or more than 90 mmHg at visit 1 and equal or more than 100 mmHg at visit 2 measured by manual cuff sphygmomanometry
• • 3. 24-hour mean diastolic blood pressure equal or more than 85 mmHg at baseline Ambulatory Blood Pressure Monitoring
• Exclusion criteria:
• • 1. mean seated systolic blood pressure equal or more than 200 mmHg and/or mean seated diastolic blood pressure equal or more than 120 mmHg
• • 2. any clinically significant hepatic impairment
• • 3. severe renal impairment
• • 4. bilateral renal artery stenosis or renal artery stenosis in a solitary kidney or post-renal transplant
• • 5. current treatment with any antihypertensive agents, whether or not prescribed for this indication, that cannot be safely stopped
• • 6. other conditions or situations that could put potential participants at unacceptable risk due to participation in this study