Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer.
Launched by LUND UNIVERSITY HOSPITAL · Oct 27, 2010
Trial Information
Current as of July 06, 2025
Completed
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Untreated metastatic colorectal carcinoma
- • Age 18 yrs or over
- • Measurable disease according to Response Evaluation Criteria in solid Tumors (RECIST criteria)
- • ECOG performance status 0 or 1
- • Life expectancy more than 3 months
- • Adequate haematological, renal and liver function
- • Tumor tissue available for determination of KRAS mutational status
- • Blood sample and paraffin embedded tumor tissue for translational research
- Exclusion Criteria:
- • Adjuvant therapy within 6 months
- • CNS metastases
- • Clinically significant atherosclerotic vascular disease
About Lund University Hospital
Lund University Hospital, affiliated with Lund University in Sweden, is a leading institution in medical research and clinical trials. Renowned for its commitment to advancing healthcare through innovative research, the hospital integrates clinical practice with academic excellence. As a sponsor of clinical trials, Lund University Hospital focuses on a wide range of therapeutic areas, striving to improve patient outcomes by rigorously evaluating new treatments and interventions. With a multidisciplinary team of expert researchers and clinicians, the hospital emphasizes ethical standards, patient safety, and scientific integrity in all its studies, contributing significantly to the global medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Stockholm, , Sweden
Sundsvall, , Sweden
Karlstad, , Sweden
Odense, , Denmark
Jönköping, , Sweden
Kalmar, , Sweden
Linköping, , Sweden
Lund, , Sweden
Umeå, , Sweden
Uppsala, , Sweden
Västerås, , Sweden
Växjö, , Sweden
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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