Comparison of Full-Field Digital Mammography With Digital Breast Tomography for Screening Call-Back Rates

Launched by AMERICAN COLLEGE OF RADIOLOGY · Nov 8, 2010

Keywords

ClinConnect Summary

Asymptomatic women 25 years and older with no history of breast cancer will be recruited from a prospective population of patients scheduled for screening mammography (Group A). A similar population of women called back from screening for 2-D FFDM-detected abnormalities will also be recruited to provide an enriched population of true-positive and false-positive 2-D FFDM and tomosynthesis cases (Group B). Pregnant women, women unable to tolerate compression of the breast associated with mammography, women with implants, and women with breasts too large to accommodate adequate positioning of ...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women 25 years of age or older;
• • No history of breast cancer;
• • Group A only: Asymptomatic and scheduled for screening mammography;
• • Group B only: Asymptomatic and recalled for diagnostic testing due to positive findings on recent screening using FFDM, completed within 30 days prior to registration (BI-RADS 0: additional imaging needed);
• • Willing to provide a written informed consent.
• Exclusion Criteria:
• • Pregnancy or intent to become pregnant;
• • Unable or unwilling to tolerate compression associated with mammography;
• • Breast implants;
• • Breasts too large to allow for adequate positioning for the DBT examination;
• • Group B only: Patients with FFDM taken at screening who are unwilling or unable to submit images to ACRIN;
• • Group B only: Unwilling to undergo tomosynthesis on both breasts as well as potentially additional diagnostic imaging based on tomosynthesis findings;
• • Unable or unwilling to complete screening and (as necessary) diagnostic imaging at same facility;
• • Tomosynthesis or mammography within 11 months prior to registration (excluding the screening mammography required for Group B).