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Search / Trial NCT01332643

Preimplantation Genetic Diagnosis (PGD) by Array Comparative Genome Hybridization (CGH) and Blastocyst Biopsy

Launched by REPROGENETICS · Apr 8, 2011

Trial Information

Current as of August 02, 2025

Terminated

Keywords

Preimplantation Genetic Diagnosis Recurrent Pregnancy Loss Infertility Genetic Screening Trisomy 21 Down Syndrome

ClinConnect Summary

Rational for the study:

The goal of this study is to determine if the strategy employed for the Test group can solve two major problems in ART, one the still low implantation rate in women of advanced maternal age, and two the frequent occurrence of multiple pregnancies resulting from solving the first problem by replacing too many embryos.

Preimplantation Genetic Diagnosis (PGD) has been proposed as a potential means to achieve these goals, but so far, the results with day 3 biopsy and FISH analysis of 5-12 chromosomes has produced contradictory results, the difference between studies be...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Couples with women 30-42 years of age
  • Follicle Stimulating Hormone (FSH) level \<11IU/L on day 3 of cycle.
  • Exclusion Criteria:
  • TESA and TESE patients
  • Couples' carriers of chromosomal or genetic diseases
  • Couples that produce less than eight antral follicles on day 2-4 of cycle
  • Patients will be excluded if they produce no blastocysts by day 5

About Reprogenetics

Reprogenetics is a leading clinical trial sponsor specializing in advanced reproductive technologies and genetic testing solutions. With a commitment to enhancing patient outcomes in reproductive health, the organization focuses on innovative approaches to preimplantation genetic diagnosis (PGD), preimplantation genetic screening (PGS), and other cutting-edge methodologies. Reprogenetics collaborates with fertility clinics and research institutions to conduct rigorous clinical trials, ensuring the highest standards of safety, efficacy, and ethical practice. Their expertise in genetic analysis and reproductive medicine positions them at the forefront of developing personalized solutions for individuals and couples seeking to optimize their reproductive options.

Locations

Lima, , Peru

Patients applied

0 patients applied

Trial Officials

Santiago Munne, PhD

Principal Investigator

Reprogenetics

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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