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Search / Trial NCT01383304

Aspirin Response in High Risk Patients With Coronary Artery Disease

Launched by UNIVERSITY OF AARHUS · Jun 27, 2011

Trial Information

Current as of July 21, 2025

Unknown status

Keywords

Platelet Aggregation Aspirin Drug Resistance Thromboxane B2 Pharmacologic Actions Platelet Aggregation Inhibitors

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Coronary artery disease verified by coronary angiogram
  • Treatment with aspirin 75 mg/d for at least the previous 7 days
  • Previous myocardial infarction more than one year ago (groups with previous myocardial infarction)
  • Type 2 diabetes mellitus treated with oral antidiabetics and/or insulin (groups with type 2 diabetes mellitus)
  • Renal insufficiency; glomerular filtration rate \<60 ml/min at the time of blood sampling (groups with renal insufficiency)
  • Exclusion Criteria:
  • Treatment with NSAIDs, clopidogrel, ticlopidine, dipyridamole, warfarin or any other drugs known to affect platelet function
  • Ischemic vascular event within the previous 12 months
  • Revascularization (angioplasty or coronary by-pass graft surgery) within the previous 12 months
  • Platelet count \<120 x 10\^9/L or \>450 x 10\^9/L
  • For patients without diabetes: fast glucose \>7 mmol/L
  • Unable to give informed consent

About University Of Aarhus

The University of Aarhus, a prestigious research institution located in Denmark, is dedicated to advancing medical science through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university fosters an environment that encourages cutting-edge research and the development of novel therapeutic interventions. Committed to ethical standards and patient safety, the University of Aarhus aims to contribute to the global body of medical knowledge while enhancing healthcare outcomes through rigorous scientific inquiry and evidence-based practices.

Locations

Aarhus N, , Denmark

Patients applied

0 patients applied

Trial Officials

Anne-Mette Hvas, MD, Ph.D

Principal Investigator

Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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