Molecular Analysis of Thoracic Malignancies

Launched by STANFORD UNIVERSITY · Jun 29, 2011

Keywords

ClinConnect Summary

This is a long-term, observational study called “Molecular Analysis of Thoracic Malignancies” at Stanford. Researchers are collecting blood, tumor tissue, normal tissue, and other body fluids to learn how cancers in the chest grow and spread. The goal is to find biological markers that predict how a cancer will behave, how well someone might respond to therapies, and potential targets for new treatments. The study aims to build a big database to better understand thoracic cancers and help with early detection in the future. No results are reported yet because this is ongoing.

Who can participate and what to expect: Adults 18 years and older with a confirmed diagnosis of non-small cell or small cell lung cancer, thymoma, thymic carcinoma, mesothelioma, or cancer of unknown primary in the chest may be eligible. Participants are identified and invited to join, then sign informed consent. The study will gather detailed medical information from records and patients through questionnaires for up to 20 years. Tissue samples (including preserved or frozen tissue and fresh tissue) and possibly blood or other fluids will be collected and stored for research in the Stanford Tissue Bank. This is purely observational, so there is no specific treatment provided by the study. Enrollment is ongoing, with oversight to ensure safety, and the work is led by Stanford University.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1.Histologically proven diagnosis of non-small cell lung cancer, small cell lung cancer, thymoma, thymic carcinoma, mesothelioma, or carcinoma of unknown primary consistent with the presentation of a primary thoracic malignancy.
• • 2.18 years of age or older.
• • 3.Ability to understand and the willingness to sign a written informed consent document.