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Search / Trial NCT01392677

Evaluation of Safety and Efficacy of Dapagliflozin in Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control on Background Combination of Metformin and Sulfonylurea

Launched by ASTRAZENECA · Jul 11, 2011

Trial Information

Current as of July 22, 2025

Completed

Keywords

Dapagliflozin Diabetes Hyperglycaemia

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Type 2 diabetes mellitus
  • Men or women age ≥ 18 years old
  • Stable dose combination of metformin and sulfonylurea
  • HbA1c ≥7.7% and ≤11.0%
  • Exclusion Criteria:
  • Type 1 diabetes mellitus or diabetes insipidus
  • Recent cardiovascular events
  • Kidney or urological disorders
  • Hepatic disorders

About Astrazeneca

AstraZeneca is a global biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative medicines across various therapeutic areas, including oncology, cardiovascular, respiratory, and autoimmune diseases. With a strong commitment to scientific research and patient-centric solutions, AstraZeneca leverages cutting-edge technology and a robust pipeline to address unmet medical needs. The company collaborates with healthcare professionals, academic institutions, and other organizations to advance clinical trials and deliver transformative therapies, aiming to improve health outcomes and enhance the quality of life for patients worldwide.

Locations

Edmonton, Alberta, Canada

Halifax, Nova Scotia, Canada

Praha, , Czech Republic

Berlin, , Germany

Quebec, , Canada

Kielce, , Poland

Lodz, , Poland

Lublin, , Poland

Warszawa, , Poland

Winnipeg, Manitoba, Canada

St. John's, Newfoundland And Labrador, Canada

Barcelona, Cataluna, Spain

Laval, Quebec, Canada

Markham, Ontario, Canada

Poznan, , Poland

Praha 6, , Czech Republic

Oviedo, Asturias, Spain

Ceske Budejovice, , Czech Republic

Kosice, , Slovakia

Dresden, , Germany

Banska Bystrica, , Slovakia

Beroun, , Czech Republic

Praha 5, , Czech Republic

Brampton, Ontario, Canada

Etobicoke, Ontario, Canada

Pirna, , Germany

Semily, , Czech Republic

Poznań, , Poland

Povazska Bystrica, , Slovakia

Neuwied, , Germany

A Coruña, , Spain

łódź, , Poland

Rimavska Sobota, , Slovakia

Falkensee, , Germany

A Coruna, Galicia, Spain

Asslar, , Germany

Sydney Mines, Nova Scotia, Canada

Kensington, , Canada

Smiths Falls, Ontario, Canada

Zgierz, , Poland

Vyskov, , Czech Republic

Jilove U Prahy, , Czech Republic

Aßlar, , Germany

Sta Coloma De Gramanet (Bcn), Catalu?A, Spain

Sta Coloma De Gramenet (Bcn), , Spain

Kensington, Prince Edward Island, Canada

Sta Coloma De Gramanet (Bcn), , Spain

Patients applied

0 patients applied

Trial Officials

Eva Johnsson, PhD, Medical Science Director

Study Director

AstraZeneca R&D, Global Medicines Development CVGI, SE-431 83 Mölndal, Sweden

Stephan Matthaei, Prof.Dr.med

Principal Investigator

Diabetes-Zentrum Quakenbruck

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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