Cryopreservation of Ovarian Cortex in Girls With Turner Syndrome
Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Aug 3, 2011
Trial Information
Current as of July 21, 2025
Active, not recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a procedure called ovarian cryopreservation, which is a way to freeze ovarian tissue to help preserve fertility in girls with Turner syndrome. Turner syndrome is a condition that affects girls and women, often leading to problems with their ovaries and making it difficult to have children. The aim of this study is to learn more about how effective this freezing process can be for girls with Turner syndrome, especially by looking at factors like the health of their ovarian tissue and other health markers.
To be eligible for this trial, girls aged between 1 and 25 years who have Turner syndrome or a related condition may participate. However, there are some important criteria: girls older than 18 must have experienced ovarian issues for less than five years, and participants need to be in good health without serious diseases like heart problems. Parents must agree for younger girls, while older participants must consent themselves. Those who qualify can expect to undergo a procedure that helps assess their ovarian health, contributing to important research on fertility preservation in this unique population.
Gender
FEMALE
Eligibility criteria
- Inclusion criteria :
- • girls aged from 1 to 25 years included,
- • with Turner syndrome or mosaic
- • patients aged more than 18 will only have ovarian insufficiency dated less than 5 years
- • without any severe disease, particularly of cardiovascular type
- • whose agreement to participate to the study has been signed by the parents
- • whose agreement to participate to the study has been signed by majority age patient
- Exclusion criteria :
- • girls aged less than one year and over 25 years old
- • if any surgery would be contra-indicated
- • ovary alone presence
- • Well-known infection by HIV, and/or HBV, and/or HCV and/or syphilis TPHA VDRL
- • No social coverage affiliate
About Assistance Publique Hôpitaux De Paris
Assistance Publique - Hôpitaux de Paris (AP-HP) is a leading public hospital system in France, renowned for its commitment to healthcare excellence and innovative medical research. As a prominent clinical trial sponsor, AP-HP plays a pivotal role in advancing medical knowledge and improving patient care through rigorous scientific investigations across a wide range of therapeutic areas. With a focus on collaboration and interdisciplinary approaches, AP-HP leverages its extensive network of hospitals and expert clinicians to facilitate high-quality clinical trials that adhere to the highest ethical and regulatory standards, ultimately aiming to translate research findings into tangible health benefits for diverse patient populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Le Kremlin Bicêtre, , France
Patients applied
Trial Officials
Lise Duranteau, MD, PhD
Principal Investigator
Assistance Publique - Hôpitaux de Paris
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials