Ovarian Reserve Testing in Female Young Adult Cancer Survivors
Launched by UNIVERSITY OF CALIFORNIA, SAN DIEGO · Aug 19, 2011
Trial Information
Current as of July 24, 2025
Active, not recruiting
Keywords
ClinConnect Summary
This clinical trial is focused on understanding the fertility potential of young adult women who have survived cancer. Many cancer treatments, especially certain types of chemotherapy, can damage the ovaries and reduce the number of eggs a woman has, which can lead to difficulties in becoming pregnant later on. The researchers want to see if specific tests can help predict whether these women will start their periods again after treatment, and how their ovarian health compares to women who have not had cancer.
To participate, women should be postmenarchal (have started their periods), have been diagnosed with cancer, and have undergone treatments that could affect their fertility, like chemotherapy or radiation, at least a year ago. Participants will keep track of their menstrual cycles for three months and might need to stop using hormonal birth control during this time. They will also undergo blood tests and pelvic ultrasounds at the beginning and end of the study to assess their ovarian health. This research aims to provide valuable information that could help young cancer survivors better understand their fertility options.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Postmenarchal
- • Cancer diagnosis
- • Prior exposure to gonadotoxic therapy, inclusive of chemothearpy, pelvic or total body irradiation, unilateral oophorectomy
- • A minimum of 1 year since completion of gonoadotoxic therapy
- • Intact uterus
- • At least one ovary
- Exclusion Criteria:
- • Estrogen receptor positive cancers
About University Of California, San Diego
The University of California, San Diego (UCSD) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a robust focus on translational medicine, UCSD leverages its interdisciplinary approach to explore groundbreaking therapies and interventions across a wide range of medical fields. The university's state-of-the-art facilities and collaboration with top-tier faculty and researchers ensure a comprehensive and ethical framework for conducting clinical trials, ultimately aiming to enhance patient outcomes and contribute to the global body of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
San Diego, California, United States
Patients applied
Trial Officials
H. Irene Su, MD MSCE
Principal Investigator
UC San Diego
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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