Ovarian Reserve Testing in Female Young Adult Cancer Survivors

Launched by UNIVERSITY OF CALIFORNIA, SAN DIEGO · Aug 19, 2011

Keywords

ClinConnect Summary

This clinical trial is focused on understanding the fertility potential of young adult women who have survived cancer. Many cancer treatments, especially certain types of chemotherapy, can damage the ovaries and reduce the number of eggs a woman has, which can lead to difficulties in becoming pregnant later on. The researchers want to see if specific tests can help predict whether these women will start their periods again after treatment, and how their ovarian health compares to women who have not had cancer.

To participate, women should be postmenarchal (have started their periods), have been diagnosed with cancer, and have undergone treatments that could affect their fertility, like chemotherapy or radiation, at least a year ago. Participants will keep track of their menstrual cycles for three months and might need to stop using hormonal birth control during this time. They will also undergo blood tests and pelvic ultrasounds at the beginning and end of the study to assess their ovarian health. This research aims to provide valuable information that could help young cancer survivors better understand their fertility options.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Postmenarchal
• • Cancer diagnosis
• • Prior exposure to gonadotoxic therapy, inclusive of chemothearpy, pelvic or total body irradiation, unilateral oophorectomy
• • A minimum of 1 year since completion of gonoadotoxic therapy
• • Intact uterus
• • At least one ovary
• Exclusion Criteria:
• • Estrogen receptor positive cancers