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Search / Trial NCT01428895

Femoral Bone Metastases

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Sep 2, 2011

Trial Information

Current as of August 20, 2025

Recruiting

Keywords

Bone Metastases Femoral Metastases

ClinConnect Summary

This clinical trial is designed to study patients with cancer that has spread to the femur (the thigh bone) and who are at high risk of experiencing a fracture. Bone metastases can cause severe pain and make it difficult for patients to move around independently. The researchers aim to understand how different treatments, such as surgery or radiotherapy (a type of radiation treatment), affect patients' pain levels, mobility, and overall quality of life.

To be eligible for this study, participants must be at least 18 years old, have a confirmed diagnosis of cancer (excluding lymphoma), and show signs of femoral metastases that put them at high risk for fractures. The trial is currently recruiting participants, and those who join will receive treatment and be monitored for their recovery over the next several months. They will share their experiences regarding pain, ability to walk, and overall well-being, which will help doctors improve care for future patients with similar conditions.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Histologically confirmed diagnosis of malignancy other than lymphoma
  • Presence of femoral metastases at high risk of pathologic fracture (Mirels' score 8 or more)
  • At least 18 years of age
  • Able to provide written informed consent
  • Able to participate in follow-up
  • Exclusion Criteria:
  • Surgical consultation for the purpose of obtaining a tissue/histological diagnosis only, not for treatment
  • Histological diagnosis of lymphoma

About University Health Network, Toronto

University Health Network (UHN), based in Toronto, is a leading academic health sciences center dedicated to advancing patient care through innovative research and education. As a prominent sponsor of clinical trials, UHN integrates cutting-edge scientific discoveries with clinical practice, facilitating the development of new therapies and treatment modalities. With a commitment to improving health outcomes, UHN collaborates with a diverse network of researchers, healthcare professionals, and industry partners, fostering an environment that prioritizes patient safety and ethical standards in clinical research. Through its extensive resources and expertise, UHN plays a pivotal role in transforming healthcare and enhancing the quality of life for patients both locally and globally.

Locations

Toronto, Ontario, Canada

Toronto, Ontario, Canada

Toronto, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Rebecca Wong, MB ChB

Principal Investigator

University Health Network, Princess Margaret Hospital

Peter Ferguson, MD

Principal Investigator

Mount Sinai Hospital, Canada

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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