PRISM Cardiac Resynchronisation Therapy (CRT) Randomised Controlled Trial
Launched by GUY'S AND ST THOMAS' NHS FOUNDATION TRUST · Sep 6, 2011
Trial Information
Current as of September 07, 2025
Unknown status
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • \>18yrs of age
- • Standard indication for CRT=P or CRT=D according to NICE criteria (Clinical symptoms of heart failure despite medical therapy, broad QRS \>120ms and significant LV dysfunction LEF \<35%)
- • Stable on optimal medical therapy for at least 3 months
- • No exclusion to pacing /ICD
- • Ischaemic or non-ischaemic aetiology
- Exclusion Criteria:
- • Any contraindication to pacing /ICD implant
- • Contraindication to MR scanning
- • Claustrophobia
- • Significant renal impairment (estimated GFR \<30)
About Guy's And St Thomas' Nhs Foundation Trust
Guy's and St Thomas' NHS Foundation Trust is a leading healthcare organization in the United Kingdom, renowned for its commitment to delivering high-quality patient care, innovative research, and clinical excellence. As a prominent academic health science center, the Trust integrates cutting-edge research with clinical practice, facilitating the translation of scientific discoveries into improved treatment options. With a diverse portfolio of clinical trials across various medical specialties, Guy's and St Thomas' NHS Foundation Trust plays a pivotal role in advancing healthcare knowledge and enhancing patient outcomes, while maintaining the highest ethical standards in research and patient safety.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Christopher Aldo Rinaldi, MD
Principal Investigator
Guy's and St Thomas' NHS Foundation Trust
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials