A Trial on the Efficacy and Safety of Virgin Coconut Oil Compared to Mineral Oil in the Treatment of Uremic Xerosis
Launched by UNIVERSITY OF THE PHILIPPINES · Sep 29, 2011
Trial Information
Current as of August 19, 2025
Completed
Keywords
ClinConnect Summary
Objectives of the Study: The general objective of this study is to assess the efficacy and safety of virgin coconut oil (VCO) compared to mineral oil as a therapeutic moisturizer for uremic xerosis. The specific objectives are as follows: 1) to determine and compare changes in the over-all dry skin score within and between treatment groups at baseline, 2 weeks-post and 4-weeks post application; 2) to quantitatively measure the following skin parameters at baseline, 2-weeks and 4-weeks post application (skin hydration using a corneometer, skin lipids using a sebumeter); 3) to determine and c...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adults undergoing maintenance hemodialysis who have mild to severe uremic xerosis
- Exclusion Criteria:
- • Patients with known hypersensitivity to the tests oils were excluded from the study as well as patients with open wounds, erosions, and ulcers on the test site and paraplegics and patients with altered sensation on the test sites.
- • Patients with xerosis associated with other dermatologic conditions antedating renal failure were excluded from the study.
About University Of The Philippines
The University of the Philippines, a premier academic institution and research hub, is dedicated to advancing healthcare through innovative clinical trials. With a strong emphasis on ethical research practices and community engagement, the university leverages its extensive resources and expertise to conduct rigorous studies that contribute to the understanding and treatment of various medical conditions. As a sponsor of clinical trials, the University of the Philippines fosters collaborations with healthcare professionals, researchers, and stakeholders to ensure the highest standards of scientific integrity and patient safety, ultimately aiming to improve health outcomes and inform public health policy.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Jacqueline Michelle G de las Alas, MD
Principal Investigator
University of the Philippines
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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