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Search / Trial NCT01457092

Self-expandable, Fully Covered Metal Stents in Biliary Strictures Due to Chronic Pancreatitis

Launched by CATHOLIC UNIVERSITY OF THE SACRED HEART · Oct 20, 2011

Trial Information

Current as of October 29, 2025

Completed

Keywords

Benign Biliary Strictures Chronic Pancreatitis

ClinConnect Summary

Endoscopic treatment of benign biliary strictures include the placement of plastic stents or Self-Expandable Metal Stents. Long term results of placement of a single plastic stent are disappointing. Better results have been obtained by endoscopic insertion of multiple plastic stents.

Biliary Self-Expandable Metal Stents used for malignant strictures are uncovered or partially covered with a plastic coating. More recently, fully covered SEMS have been developed and are now available on the market and due to their removability are proposed also for benign indications.

Uncovered and partiall...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. age ≥18 years,
  • 2. symptomatic (persistent cholestasis, jaundice, cholangitis) common bile duct strictures secondary to CP, that persist 3 months or more after placement of a single 10 French plastic stent and
  • 3. patient unfit for surgery (portal cavernomatosis, comorbidities) or patient refusal of surgery.
  • Exclusion Criteria:
  • 1. benign biliary strictures secondary to compression from a pancreatic pseudocyst;
  • 2. patients with associated pancreatic neoplasia
  • 3. ongoing alcohol abuse (ethanol \> 80 g/day).

About Catholic University Of The Sacred Heart

The Catholic University of the Sacred Heart is a prestigious academic institution in Italy, renowned for its commitment to advancing medical research and education. With a strong emphasis on ethical standards and community well-being, the university actively engages in clinical trials that contribute to innovative healthcare solutions. Its multidisciplinary approach leverages expertise from various fields, fostering collaborations that enhance the quality and impact of research. The university is dedicated to improving patient outcomes through rigorous science and compassionate care, aligning with its mission to serve the greater good.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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