Study of RO6807952 in Patients With Diabetes Mellitus Type 2

Launched by HOFFMANN-LA ROCHE · Jan 19, 2012

Keywords

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Gender

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Eligibility criteria

• Inclusion Criteria:
• • Adult patients \>/= 18 and \</=70 years of age
• • Diagnosis of diabetes mellitus, type 2 for at least 3 months
• • Treated with a stable dose of metformin
• • Hemoglobin A1c \>/=7.0% and \</=10.5% at screening
• • Fasting plasma glucose \</=240 mg/dL at screening
• • Body mass index \>/=27 kg/m2 and \</=42 kg/m2 at screening
• • Willing and able to maintain existing diet and exercise habits throughout the study
• • C-peptide \>1.5 ng/mL at screening
• Exclusion Criteria:
• • History of significant liver or kidney disease
• • History of uncontrolled hypertension
• • History of significant cardiovascular disease
• • History of significant diabetic complications
• • History of significant gastrointestinal conditions
• • History of weight loss surgery or procedures involving the gastrointestinal tract
• • History of chronic or acute pancreatitis

Trial Officials