Lung Ultrasound to Diagnose Transient Tachypnea of the Newborn (TTN) Versus Respiratory Distress Syndrome (RDS) in Neonates

Launched by ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · Jan 24, 2012

Keywords

ClinConnect Summary

Respiratory distress is a common reason for admission to the neonatal intensive care unit (NICU) for both preterm and full term newborns. TTN and RDS are the two most common diagnoses associated with respiratory distress. Due to their similar clinical presentations, it is often difficult to differentiate the two diseases clinically. Currently chest radiography is used to differentiate between TTN and RDS, however, radiographic findings are not always definitively diagnostic.

In preliminary studies, lung ultrasonography has been shown to be a useful tool in diagnosing both TTN and RDS. Howe...

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Eligibility criteria

• Inclusion Criteria:
• • gestational age ≥ 28 weeks
• * symptoms of respiratory distress defined as:
• • tachypnea (respiratory rate \> 60 breaths per minute)
• • FiO2 requirement \>21%
• • intercostal/subcostal retractions
• • grunting and/or nasal flaring
• • If clinically warranted, a chest x-ray will be done as part of the workup for respiratory distress; these patients with CXR will be included in the study.
• • Inclusion criteria for the control group will be gestational age ≥ 28 weeks with no symptoms of respiratory distress (defined above).
• Exclusion Criteria:
• • neonates with prenatally diagnosed structural cardiac disease
• • major multiple congenital anomalies
• • other causes of respiratory distress that are not RDS or TTN (e.g. pneumothorax, CCAM or pneumonia).