Evaluation of Analgesia Nociception Index (ANI) During Propofol/Remifentanil and Sevoflurane/Remifentanil Anesthesia
Launched by UNIVERSITY HOSPITAL SCHLESWIG-HOLSTEIN · Jan 30, 2012
Trial Information
Current as of May 14, 2025
Unknown status
Keywords
ClinConnect Summary
Monitoring Antinociception during general anesthesia is still a big challenge in the field and has not become clinical routine yet. Recently, for the Surgical Pleth Index SPI a benefit for the patient in terms of reduction of remifentanil use, less unwanted effects and shorter recovery from anesthesia was reported. However, there are new variables like the ANI that are developed to measure antinociception during anesthesia.
In the present study the investigators want to evaluate, whether ANI detects a painful tetanic stimulus during general anesthesia using propofol or sevoflurane and diff...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • age between 18- 65 years,
- • ASA physical status I or II,
- • elective surgery in general anesthesia planned,
- • written informed consent
- Exclusion Criteria:
- • pregnancy,
- • history of cardiac arrhythmia,
- • presents of any neuromuscular or neurologic disease,
- • use of CNS-active medication or abuse of alcohol/illicit drugs -
About University Hospital Schleswig Holstein
University Hospital Schleswig-Holstein (UKSH) is a leading academic medical center in Germany, renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent institution, UKSH integrates cutting-edge medical research with comprehensive patient care, fostering an environment that promotes the development of novel therapeutic strategies. With a multidisciplinary approach and a strong emphasis on collaboration, UKSH is dedicated to enhancing clinical outcomes and contributing to the global medical community through rigorous scientific inquiry and the translation of research findings into practice.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Kiel, , Germany
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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