Proteogenomic Monitoring and Assessment of Kidney Transplant Recipients

Launched by NORTHWESTERN UNIVERSITY · Feb 9, 2012

Keywords

ClinConnect Summary

This clinical trial is studying how to better monitor kidney transplant recipients for signs of rejection and other problems that can affect the health of the transplanted kidney. Researchers want to find specific markers in blood, urine, and kidney tissue that can help detect issues like acute rejection and chronic damage earlier and more safely than current methods. By identifying these markers, doctors hope to improve treatment and outcomes for patients with kidney transplants.

To participate in this study, you must be at least 18 years old and have received a kidney transplant from either a living or deceased donor. You will need to agree to take part in the study and provide consent. Participants will undergo regular monitoring through standard kidney biopsies, as well as blood and urine tests. This research aims to make it easier and safer to assess kidney health after transplantation, ultimately helping to prevent serious complications and improve the longevity of the kidney graft.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Male and female recipients of all races, ≥18 years of age.
• • 2. Patients undergoing primary or subsequent deceased-donor or living donor kidney transplantation.
• • 3. Subject and/or guardian must be able to provide informed consent.
• • 4. Subject and/or guardian must be able to comply with the study protocol.
• Exclusion Criteria:
• • 1. Need for combined organ transplantation with an extra-renal organ and/or islet cell transplant.
• • 2. Recipients of previous non-renal solid organ and/or islet cell transplantation.
• • 3. Infection with HIV.
• • 4. Inability or unwillingness of a participant and/or guardian to provide informed consent