Cryopreservation of Ovarian Tissue

Launched by WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY · Mar 19, 2012

Keywords

ClinConnect Summary

This clinical trial is studying a method called cryopreservation, which involves freezing ovarian tissue to help women who are at risk of losing their fertility due to cancer treatments or medical conditions. The goal is to improve techniques for freezing and thawing this tissue and maturing immature eggs in a lab, so that women can have a chance to conceive a child that is genetically related to them in the future.

Women between the ages of 0 and 45 who are premenopausal and are facing treatments that may cause premature menopause, such as certain types of cancer therapies or surgeries that involve removing the ovaries, may be eligible to participate. Participants will undergo a surgical procedure to take a small piece of ovarian tissue, which will then be frozen for potential future use. It's important that participants are in good health and have received medical clearance for the surgery. This trial is currently recruiting participants, so if you or someone you know fits the criteria and is interested in preserving fertility, this could be a valuable opportunity.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Females 0-45 years of age who are premenopausal
• • Treatment plan that will likely result in premature menopause or premature ovarian failure
• * This includes patients receiving:
• • Cancer treatment with abdominal pelvic irradiation and/or high dose chemotherapy
• • Surgery that requires removal of ovaries for medical condition or disease, e.g. Prophylactic oophorectomy in BRCA patients
• • Patient is unable or unwilling to pursue fertility preservation by freezing oocytes or embryos.
• • Previous treatment for cancer is acceptable if patient still has ovarian function
• • Patient is medically stable enough to undergo surgery (cleared for anesthesia)
• Exclusion Criteria:
• • Patients not meeting the above criteria
• • Patients who have not received medical clearance from their physicians to undergo surgery
• • Patients already experiencing menopause.