Does Flushing the Uterine Cavity With Follicular Fluid After Ovum Pick-up Improve Implantation Rates in ICSI Cycles?
Launched by NAWARA MOHAMED HASHISH · Mar 23, 2012
Trial Information
Current as of June 26, 2025
Completed
Keywords
ClinConnect Summary
Introduction:
Looking at the process of IVF, we found that we only make use of the ovum and sperm and we neglect completely the valuable effect of the follicular fluid which is currently attracting a lot of attention. Several studies revealed a pivotal role played by this fluid in the process of fertilization and implantation as it is rich in growth factors as stem cell factor, transforming growth factor and insulin growth factor and cytokines (1,2).
Macciò study confirmed that follicular fluid (FF) contains factors that induce immunosuppression and explained that the immunosuppressive ac...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • 1. Maternal age ranges from 20-38 years.
- • 2. Basal FSH \< 10 mIU/ml.
- • 3. BMI \< 35 kg/m2.
- • 4. Estradiol level \> 1000 at the day of HCG administration.
- • 5. Estradiol level \< 4000 at the day of HCG administration.
- Exclusion Criteria:
- • 1. Presence of Endometriosis.
- • 2. Presence of Hydrosalpinx.
- • 3. Presence of vaginal infection.
- • 4. Presence of galactorrhea.
- • 5. Presence of hormonal disorders.
- 6. Severe male factor infertility:
- • Sperm Count \< one million. Marked malformation
- • 7. history of recurrent abortion.
About Nawara Mohamed Hashish
Nawara Mohamed Hashish is a dedicated clinical trial sponsor committed to advancing medical research and improving patient outcomes. With a strong focus on ethical practices and regulatory compliance, Nawara leads innovative studies aimed at evaluating the safety and efficacy of novel therapeutic interventions. Her expertise encompasses a wide range of therapeutic areas, and she collaborates closely with healthcare professionals, regulatory agencies, and research institutions to ensure rigorous trial design and execution. Nawara's mission is to contribute to the scientific community through high-quality clinical trials that drive meaningful advancements in healthcare.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Trial Officials
Nawara Mohamed Hashish, MD
Principal Investigator
Department of Obstetrics and Gynecology,Cairo University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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