Contraceptive Pill and Hormonal Vaginal Ring in Women With Polycystic Ovary Syndrome
Launched by UNIVERSITY OF OULU · Apr 27, 2012
Trial Information
Current as of July 21, 2025
Unknown status
Keywords
ClinConnect Summary
The study population consists of women of reproductive age with PCOS, no wish of pregnancy and no other contraindications to hormonal contraceptives.
The volunteer subjects will be recruited from hospital's patient files with PCOS (IC diagnosis E.28.2).
Methods Sample size Our previous study comparing the metabolic effects of the same preparations (Mercilon and Nuvaring) in young healthy women shown an significant decrease of 1.65 (SD 1.68)in the Matsuda index at 9 weeks of treatment with oral contraceptive pill. Power analysis indicated that 14 women would be needed in both groups to rev...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • women aged between 18 to 40 years
- • diagnosed PCOS (Rotterdam criteria)
- • healthy, no medications
- • no use of hormonal contraceptives or wash-out period of at least two months
- • no contraindications to hormonal contraception
- Exclusion Criteria:
- • regular smoking
- • excessive alcohol use
- • pregnancy or breastfeeding
- • oversensitivity to active ingredients
- • migraine with focal aura
- • severe or multiple risk factors to thrombosis
- • diagnosed or suspected cancer
- • diagnosed or suspected estrogen-dependent tumor
- • acute or chronic hepatocellular disease -related abnormal liver function
- • hepatic adenomas or carcinomas
- • undiagnosed abnormal vaginal bleeding
About University Of Oulu
The University of Oulu, located in Finland, is a leading research institution known for its commitment to advancing scientific knowledge and innovation in various fields, including health sciences. As a clinical trial sponsor, the University of Oulu leverages its extensive academic expertise, state-of-the-art facilities, and collaborative networks to conduct rigorous and ethically sound clinical research. The university emphasizes interdisciplinary approaches and strives to translate research findings into practical applications that improve patient outcomes and contribute to public health. Through its clinical trials, the University of Oulu aims to foster advancements in medical science while adhering to the highest standards of integrity and compliance.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Oulu, , Finland
Patients applied
Trial Officials
Laure C Morin-Papunen
Principal Investigator
University of Oulu
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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