Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate

Launched by CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS · May 16, 2012

Keywords

ClinConnect Summary

This clinical trial is focused on understanding the genetic factors that contribute to certain reproductive disorders and conditions like cleft lip and/or palate. Some of the conditions being studied include Kallmann syndrome, which affects the sense of smell and puberty, as well as polycystic ovarian syndrome and cleft lip/palate. By exploring these genetic connections, researchers hope to gain insights that could lead to better treatment options or preventive measures in the future.

If you or a family member have one of the conditions mentioned, such as hypogonadotropic hypogonadism or precocious puberty, you might be eligible to participate. The trial is currently open for recruitment and welcomes individuals of all ages and genders. Participants can expect to provide some personal and family medical history and may undergo genetic testing. However, people with certain health issues, such as acute illnesses or chronic drug use, will not be able to join. This study is an opportunity to contribute to important research that could improve understanding and care for these conditions.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria:(any of the following conditions)
• • hypogonadotropic hypogonadism
• • Kallmann syndrome
• • adult-onset hypogonadotropic hypogonadism
• • hypothalamic amenorrhea
• • polycystic ovarian syndrome
• • primary gonadal failure
• • precocious puberty
• • cleft lip/palate
• • family members of the above groups
• Exclusion Criteria:
• • acute illness/hospitalization
• • pituitary tumors
• • iron overload (hemochromatosis)
• • infiltrative diseases (sarcoidosis)
• • chronic alcohol abuse
• • illicit drug use
• • anabolic steroid abuse