Effect of Salt Restriction on Renin Activation

Launched by TURKISH SOCIETY OF HYPERTENSION AND RENAL DISEASES · Jun 22, 2012

Keywords

ClinConnect Summary

The present study is carried out with the subjects who are chosen among the nursing home residents in İzmir. The subjects were randomized to 2 groups and while one of these groups had low salt diet (50mmol), the other group had normal salt diet (250mmol) for 3 weeks. Subjects had normal salt diet in their daily routine life for the following 2 weeks. According to crossover nature of the study, the group that had normal salt diet at the first 3 weeks of study had low salt diet at the last 3 weeks of the study. The other group that had low salt diet had the normal salt diet at the last 3 week...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Subjects who are 50 years and older
• • Subjects whose systolic blood pressure is ≥ 140 mmHg
• • Subjects whose diastolic blood pressure is ≥ 90 mmHg
• • Subjects who is normal weighted defined as body mass index \< 25 or who is obese defined as body mass index \> 30
• • Subjects who have intellectual capacity to adapt diets and 24 hour urine collection
• • Informed about the study and consented to include the study
• Exclusion Criteria:
• • Known heart failure
• • Known renal failure
• • Known chronic liver disease
• • Antihypertensive drug use
• • nonsteroidal anti inflammatory (NSAI) drug use