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Search / Trial NCT01672346

PV Reconnection After PVAI at Different Power Settings and Adenosine Provocation

Launched by TEXAS CARDIAC ARRHYTHMIA RESEARCH FOUNDATION · Aug 21, 2012

Trial Information

Current as of July 06, 2025

Unknown status

Keywords

Paf

ClinConnect Summary

Background:

The efficiency of catheter ablation in drug-refractory atrial fibrillation (AF) is compromised by high incidence of post-ablation AF recurrences requiring multiple ablation procedures (1). Post-PVAI (pulmonary vein antrum isolation) AF recurrence is mostly due to reconnection of the previously isolated PVs (2). Earlier studies have revealed that elimination of dormant PV conduction revealed by adenosine-provocation ensures better outcome as reconnection mostly happens due to presence of incompletely ablated tissue and identification and complete ablation decrease chance of recu...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Age ≥ 18 years
  • 2. Patients presenting with drug-refractory PAF undergoing first ablation
  • 3. Ability to understand and provide signed informed consent
  • Exclusion Criteria:
  • 1. Previous catheter ablation or MAZE procedure in left atrium
  • 2. Reversible causes of atrial arrhythmia such as hyperthyroidism, sarcoidosis, pulmonary embolism etc

About Texas Cardiac Arrhythmia Research Foundation

The Texas Cardiac Arrhythmia Research Foundation is a leading clinical trial sponsor dedicated to advancing the understanding and treatment of cardiac arrhythmias. With a focus on innovative research and collaboration, the foundation conducts rigorous clinical studies aimed at improving patient outcomes and enhancing therapeutic strategies. By leveraging cutting-edge technology and a team of experienced professionals, the foundation strives to translate scientific findings into effective clinical practices, ultimately contributing to the broader field of cardiovascular health. Through its commitment to excellence and patient-centered care, the Texas Cardiac Arrhythmia Research Foundation plays a pivotal role in shaping the future of arrhythmia management.

Locations

Austin, Texas, United States

Austin, Texas, United States

Patients applied

0 patients applied

Trial Officials

Andrea Natale, MD

Principal Investigator

TCAI

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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