Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure
Launched by UNIVERSITY OF CHICAGO · Sep 4, 2012
Trial Information
Current as of August 24, 2025
Completed
Keywords
ClinConnect Summary
Respiratory failure is often treated with endotracheal intubation and mechanical ventilation. Although, the institution of mechanical ventilation is considered life saving, the associated complications of tracheal stenosis, ventilator associated pneumonia, barotrauma , and neuromuscular weakness are not without considerable morbidity and mortality.
Non-invasive ventilation has demonstrated significant benefit in patients with hypercapnic respiratory failure from COPD, acute cardiogenic pulmonary edema, and hypoxemic respiratory failure in immunocompromised patients.
Despite the advantages...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients aged ≥18 years of age who require noninvasive ventilation via facemask for \>8hours
- • Intact airway protective gag reflex
- • Able to follow instructions
- Exclusion Criteria:
- • Cardiopulmonary arrest
- • Glasgow coma scale \<8
- • Absence of airway protective gag reflex
- • Elevated intracranial pressure
- • Tracheostomy
- • Upper airway obstruction
- • Pregnancy.
- • Patients who refuse to undergo endotracheal intubation, whatever the initial therapeutic approach
About University Of Chicago
The University of Chicago is a prestigious research institution renowned for its commitment to advancing medical science through innovative clinical trials. With a robust infrastructure that supports multidisciplinary collaboration, the University actively engages in cutting-edge research across various therapeutic areas. Its dedicated team of experienced investigators and state-of-the-art facilities enable the University of Chicago to conduct rigorous clinical studies aimed at improving patient outcomes and translating scientific discoveries into tangible healthcare solutions. The institution prioritizes ethical standards and patient safety, ensuring that all trials adhere to the highest regulatory guidelines and best practices in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Chicago, Illinois, United States
Patients applied
Trial Officials
John P Kress, MD
Principal Investigator
University of Chicago
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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