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Search / Trial NCT01742702

HaemoDYNAMICs in Primary and Secondary Hypertension

Launched by TAMPERE UNIVERSITY · Dec 3, 2012

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Blood Pressure Hypertension Arterial Stiffness Cardiac Output Vascular Resistance Pulse Wave Reflection Head Up Tilt

ClinConnect Summary

This clinical trial, called HaemoDYNAMICs in Primary and Secondary Hypertension, is studying how blood flow and pressure change in people with high blood pressure, specifically looking at both primary hypertension (the most common type) and secondary hypertension (caused by other health issues like kidney diseases or hormonal problems). Researchers will use non-invasive methods, which means no needles or surgery, to measure these changes in different positions, such as lying down and standing up. They will also compare the results with those from individuals suffering from chronic fatigue syndrome.

To participate in this study, you need to be an independent adult who lives in the community and has high blood pressure (either primary or secondary). They are also looking for healthy individuals with normal blood pressure, people with aortic stenosis (a heart condition), and participants of Ironman Triathlon competitions. Unfortunately, those who are pregnant, have very low blood pressure, or are allergic to the test substances cannot join. If eligible, participants can expect a thorough and safe examination of their heart and blood flow, contributing valuable information that can help improve treatments for high blood pressure.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Independent, community-dwelling adults
  • Hypertensive subjects (primary or secondary hypertension)
  • Normotensive control subjects
  • Subjects with aortic stenosis (subgroup "aortic stenosis")
  • Participants of Ironman Triathlon competition
  • Exclusion Criteria:
  • Pregnancy
  • Systolic blood pressure \<90 mmHg
  • Allergies to test compounds

About Tampere University

Tampere University, a leading research institution in Finland, is dedicated to advancing scientific knowledge and innovation through rigorous clinical trials. With a strong emphasis on interdisciplinary collaboration, the university leverages its expertise in health sciences, engineering, and social sciences to conduct impactful research that addresses pressing health challenges. Tampere University is committed to ethical research practices and fostering partnerships with healthcare providers and industry stakeholders to translate findings into meaningful clinical applications, ultimately enhancing patient care and public health outcomes.

Locations

Tampere, Southern Finland, Finland

Tampere, Southern Finland, Finland

Patients applied

0 patients applied

Trial Officials

Ilkka Pörsti, MD, PhD

Principal Investigator

Tampere University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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