Intra-articular Betamethasone and the Hypothalamic-pituitary-adrenal Axis
Launched by THE NAZARETH HOSPITAL, ISRAEL · Feb 23, 2013
Trial Information
Current as of August 29, 2025
Completed
Keywords
ClinConnect Summary
Consecutive patients attending the rheumatology or orthopedic clinic with osteoarthritic knee pain, not responding satisfactorily to medical or physical therapy were allocated to group-1 after consent and given IACI of 6 mg of betamethasone acetate/betamethasone sodium phosphate. Following completion of this part, consecutive age- and sex-matched patients were allocated to group-2 and given intra-articular injection of 60 mg of sodium hyaluronate. Just prior to the knee injection and 1, 2, 3, 4 and 8 weeks later, patients had 1 µg adrenocorticotropin hormone (ACTH) stimulation test. Seconda...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Osteoarthritis of the knee
- Exclusion Criteria:
- • Had steroids in the last 3 months. Allergic to steroids
About The Nazareth Hospital, Israel
Nazareth Hospital in Israel is a prominent healthcare institution dedicated to delivering high-quality medical services and advancing clinical research. With a strong emphasis on patient-centered care, the hospital integrates innovative medical practices and cutting-edge technology to enhance treatment outcomes. As a clinical trial sponsor, Nazareth Hospital is committed to fostering research initiatives that contribute to medical knowledge and improve therapeutic options for diverse patient populations. The hospital collaborates with multidisciplinary teams and adheres to stringent ethical standards to ensure the safety and efficacy of trial protocols, aiming to make significant contributions to the field of medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
George Habib, M.D.
Principal Investigator
Nazareth Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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