Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)

Launched by THE ROGOSIN INSTITUTE · Feb 28, 2013

Keywords

ClinConnect Summary

The RENAL AID trial is a study designed to collect important information about different types of kidney diseases, including diabetes-related kidney issues and conditions caused by autoimmune diseases like lupus. Researchers aim to gather data from a wide range of individuals—some with kidney diseases and some healthy—to better understand what factors might influence the progression of these diseases and how patients respond to treatments. This information will help identify non-invasive ways to predict kidney problems without needing invasive procedures like biopsies.

To be eligible for this trial, participants need to be at least 18 years old and willing to give their consent to take part. There are specific groups people can fall into, such as those needing a kidney biopsy for medical reasons, those who have diabetes and kidney disease but haven't had a biopsy, or those who have had a kidney transplant and require monitoring. Participants can expect to contribute to an important database that could lead to better kidney disease management in the future. It's essential for potential participants to know that they must be able to provide informed consent, meaning they understand what the trial involves and agree to participate.

Gender

ALL

Eligibility criteria

• Key Inclusion Criteria:
• All Groups:
• • Males or females
• • 18 years of age and older
• • Willing and able to provide informed consent
• Native Biopsy Tissue Group:
• • - Require an initial kidney biopsy for medical necessity
• Native Kidney, Non-tissue Group:
• • Previously had a kidney biopsy and the tissue is not stored in this biorepository; or
• • Have diabetes and kidney disease and have not had a kidney biopsy
• Allograft Tissue Group:
• • - Have undergone a renal transplant and require a transplant biopsy for either surveillance or "for-cause" indications.
• Key Exclusion Criteria for all Groups:
• • - Inability to provide informed consent.