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Search / Trial NCT01803906

Tissue Sample Study for Mitochondrial Disorders

Launched by COLUMBIA UNIVERSITY · Mar 1, 2013

Trial Information

Current as of July 01, 2025

Enrolling by invitation

Keywords

Mitochondrial Disorder Mitochondria Oxidative Phosphorylation Oxidative Phosphorylation Disorders Respiratory Chain Disorders Mitochondrial Disease Melas Kearns Sayer Narp Mngie Lhon Mitochondrial Depletion Syndrome Leigh's Disease

ClinConnect Summary

Presently, the investigators know of about 200 mitochondrial disorders. The investigators know that there are about 1,300 genes responsible for mitochondrial function. Thus, there are a lot of mutated genes to be discovered out there. Currently, most patients with suspected or known mitochondrial disorders do not have genetic confirmation of the disease.

The goal of this project is to perform biochemical and DNA analysis on tissue samples of patients with mitochondrial disorders to find new genes that might be involved in mitochondrial dysfunction.

Leftover patient tissue samples will be ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients suspected of having a mitochondrial disorder
  • Patients who may carry a genetic mutation or be related to someone with a genetic mutation which may cause a mitochondrial disorder
  • Exclusion Criteria:
  • Patients who are not suspected of having a mitochondrial disorder

About Columbia University

Columbia University, a prestigious Ivy League institution located in New York City, is a leading sponsor of clinical trials dedicated to advancing medical research and improving patient care. With a robust network of research facilities and a commitment to innovation, Columbia University collaborates with a diverse range of healthcare professionals and researchers to explore groundbreaking therapies and treatment methodologies. The university's clinical trials encompass various fields, including oncology, neurology, and public health, aiming to translate scientific discoveries into effective clinical applications. Columbia University is dedicated to maintaining the highest ethical standards and regulatory compliance, ensuring the safety and well-being of trial participants while contributing to the global body of medical knowledge.

Locations

New York, New York, United States

Patients applied

0 patients applied

Trial Officials

Michio Hirano, MD

Principal Investigator

Columbia University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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