Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal

Launched by NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH (NIDCR) · Mar 5, 2013

Keywords

ClinConnect Summary

This clinical trial is looking at the removal of wisdom teeth, also known as third molars. Researchers want to collect the wisdom teeth and surrounding tissue that are usually discarded after surgery. This study aims to help dentists at the National Institutes of Health improve their surgical skills while also gathering important information for future oral health research. If you are between the ages of 16 and 50 and need to have your wisdom teeth removed, you may be eligible to participate.

Participants in this study will have at least three visits: one to check your health and dental needs, one for the surgery to remove your wisdom teeth, and a follow-up visit to ensure you are healing properly. During the surgery, your wisdom teeth and tissue will be collected for research purposes. After the surgery, you will receive medication to help with pain and can reach out to a dentist if you have any concerns. Most people will have their final check-up about one to three weeks after the surgery, but if any issues arise, additional visits will be scheduled as needed.

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA:
• • Ages greater than or equal to 16-50 years
• • Clinical evidence of need for third molar extraction as determined by medical, dental, and radiographic evaluation by a NIDCR oral surgeon
• • Willing to allow for the collection of extracted waste tissue (e.g., teeth, alveolar bone, excessive gingival tissue) to be used for research
• • In good general health as defined by the American Society of Anesthesiologists (ASA) status I or II
• • Able to understand and sign an informed consent
• EXCLUSION CRITERIA:
• • Pregnant or nursing women
• • Unable to have third molar extraction as determined by NIDCR surgeon/dentist, due to medical conditions (beyond ASA I or II), complexity of the surgery, or history that precludes safe outpatient conscious sedation. These clinical decisions will be based on the risks and benefits related to the surgery.