Investigation of GM Pathology Using Ultra High Field (7T) MRI Scanner

Launched by UNIVERSITY OF NOTTINGHAM · Mar 5, 2013

Keywords

ClinConnect Summary

Purpose for this study:

This research group has previously investigated the usefulness of a powerful new MRI scanner and have found that the 7 Tesla MRI is able to provide detailed structural images of the cortex of the brain which can uncover pathology such as cortical demyelinating lesions in MS patients. Multiple sclerosis (MS) affects the grey matter as well as the white matter of the brain and spinal cord. However as white matter lesions are more easily visible both pathologically and on MRI, therefore most MS research has focused on white matter demyelination. The investigators would...

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • Patients with MS or other neurological disease which already had at least 1 MRI scan.
• • Healthy volunteers which had no indication of neurological disease in the past.
• • Do not have significant cognitive impairment and are able to give consent.
• • Will not have any contraindication for MR imaging
• • Are able to lie flat for up to 60 mins.
• • Age 25 and over.
• Exclusion criteria:
• • Pregnancy
• • Have any implants in the body.
• • Have aneurysm clips.
• • Have pacemaker or artificial heart valve.
• • Have foreign bodies in their body (e.g. shrapnel).