Magnetic Resonance & Optical Spectroscopy Validation

Launched by ADVENTHEALTH TRANSLATIONAL RESEARCH INSTITUTE · Apr 4, 2013

Keywords

ClinConnect Summary

This clinical trial is studying new ways to use special imaging techniques called magnetic resonance and optical spectroscopy to understand how our bodies use energy. The goal is to improve these techniques, which could help doctors learn more about health and disease in the future. They are currently looking for participants who are healthy adults aged between 18 and 89, weigh less than 350 pounds, can walk 50 yards without stopping, and are comfortable being in an MRI machine for up to two hours.

If you join this study, you will undergo some imaging procedures to gather information about your body’s energy use. It's important to note that certain conditions, such as having metal medical devices in your body or a history of blood clots, may prevent you from participating. Additionally, women who are pregnant or planning to become pregnant soon, as well as those with specific health issues, will not be eligible. This trial is a great opportunity to contribute to medical research while learning more about your own health!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female
• • Age 18 - 89
• • Healthy (self assessed)
• • Weight under 350lbs
• • Able to walk 50 yards without stopping
• • Able to travel to hospital for study visits
• • Able to follow a 3-step command
• • Able to remain in magnetic resonance (MR) scanner for up to 2 hours
• Exclusion Criteria:
• • Have internal metal medical devices, including cardiac pacemakers, aortic or cerebral aneurysm clips, artificial heart valves, ferromagnetic implants, shrapnel, wire sutures, joint replacements, bone or joint pins/rods/screws, metal fragments in your eye, or non-removable jewelry such as rings.
• • Are unwilling or unable to complete the imaging procedures for the duration of the magnetic resonance imaging (MRI) scan due to claustrophobia or other reason.
• • Serious mental illness that might preclude subject's ability to comply with study treatment
• • Are pregnant or plan on becoming pregnant in the next 8 weeks.
• • History of deep vein thrombosis (DVT) or pulmonary embolism (PE)
• • Varicose Veins
• • Known genetic factor (Factor V Leiden, etc.) or hypercoagulable state, including cancer, leukemia - such as chronic myelocytic leukemia (CML), hemoglobinopathies - such as sickle-cell disease and multiple myeloma and other proteinopathies.
• • Diagnosed peripheral arterial or vascular disease
• • Family history of primary DVT or PE
• • Peripheral neuropathy
• • History of chronic venous stasis or lower extremity edema
• • Female taking hormonal birth control (oral or otherwise) AND smoker