TaTME Versus Open Intersphincteric Resection After Neoadjuvant Concurrent Chemoradiotherapy.

Launched by OSAMA MOHAMMAD ALI ELDAMSHETY · Apr 17, 2013

Keywords

ClinConnect Summary

During the period between April 2013 and July 2019, a non-randomized controlled study was performed at two tertiary centers; Oncology Centre of Mansoura University and Policlinico Umberto Primo surgery department of SAPIENZA university of Rome after referral from the clinical oncology and nuclear medicine department. After diagnosis of ultralow rectal cancer, a written informed consent was obtained from patients after full explanation of the procedure, the likely outcome and the potential complications that may occur. Digital rectal examination was conducted to assess the distance of lower ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with low rectal carcinoma(The lowest margin of tumor located 3 cm from anal verge ; ≤ 2 cm from dentate lines; 1 cm from anorectal rings.
• • Local spread restricted to the rectal wall or the internal anal sphincter.
• • Adequate preoperative sphincter function and continence.
• • Absence of distant metastasis.
• Exclusion Criteria:
• • Contraindications to major surgery and American Society of Anesthesiologists (ASA) Physical Status scoring 4.
• • Metastatic rectal cancer.
• • Those in Dukes stage D (T4 lesion).
• • Undifferentiated tumours.
• • Local infiltration of external anal sphincter or levator ani muscles.
• • Tumor located more than 2 cm above the dentate line.
• • Presence of fecal incontinence.
• • Patients unwilling to take part in the study.