Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia
Launched by UNIVERSITY HOSPITAL, BASEL, SWITZERLAND · Apr 18, 2013
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is focused on finding better ways to detect a condition called exercise-induced myocardial ischemia, which happens when the heart doesn't get enough blood during physical activity. Researchers are studying new biochemical markers and electrocardiogram (ECG) patterns, both on their own and alongside the standard 12-lead exercise ECG, to see how well they can identify this heart issue. Additionally, they want to understand if these new methods can help predict long-term risks of serious heart problems, like heart attacks or death from heart disease.
To be eligible for this study, participants should be between the ages of 65 and 74 and have symptoms that suggest they might experience heart problems during exercise. Patients who are younger than 18, pregnant, or unable to give consent cannot participate. Those who join the trial can expect to undergo tests that include a special heart imaging technique called SPECT, which helps doctors see how well blood flows to the heart during exercise. This trial is currently recruiting participants, and the findings could lead to improved methods for diagnosing heart conditions in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients presenting with suspected exercise-induced myocardial ischemia referred for rest/ergometry myocardial perfusion SPECT
- Exclusion Criteria:
- • Age \< 18 years
- • Pregnancy
- • Unable or unwilling to give informed consent
- • Symptoms at rest or minor exertion
About University Hospital, Basel, Switzerland
The University Hospital Basel, Switzerland, is a leading academic medical center renowned for its commitment to cutting-edge research and innovative patient care. As a prominent clinical trial sponsor, the hospital leverages its extensive expertise and state-of-the-art facilities to advance medical knowledge and therapeutic options across various disciplines. With a collaborative approach that integrates clinical practice and scientific inquiry, the University Hospital Basel fosters an environment conducive to rigorous clinical trials, ensuring the highest standards of safety and efficacy. Its strategic focus on patient-centered research aims to translate scientific discoveries into tangible health solutions, benefiting both local and global communities.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Basel, , Switzerland
Patients applied
Trial Officials
Christian Mueller, Prof. Dr. MD
Principal Investigator
University Hospital, Basel, Switzerland
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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