Residual Curarization and Its Incidence at Tracheal Extubation in China

Launched by XINMIN WU · Jun 5, 2013

Keywords

ClinConnect Summary

This is a prospective, multi-site, anesthesiologist and PACU nurse TOF-Watch SX® blinded observational study of surgical patients undergoing elective laparoscopic or open abdominal procedures requiring general anesthesia and non-depolarizing neuromuscular blockade. There are two temporal aspects to the data collection: a prospective data collection in the OR and PACU; and a retrospective chart review one week after hospital discharge.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age≥18;
• • American Society of Anesthesiologists(ASA) class 1-3;
• • Scheduled for elective open or laparoscopic abdominal surgery that is anticipated to last less than 4 hours;
• • Administration of general anesthesia and ≥ 1 dose of non-depolarizing neuromuscular blockers for endotracheal intubation or maintenance of neuromuscular blockade;
• • Planned for extubation to occur in the OR;
• • Signed informed consent.
• Exclusion Criteria:
• • Redo surgery on the same hospital admission;
• • Pre-established need or expected to require post-operative mechanical ventilation;
• • Conditions, surgical procedures, or participant positioning that may interfere with TOF-Watch SX® operation, calibration, or accuracy;
• • Anesthesiologist use of objective neuromuscular monitoring during surgery (e.g. mechanomyography, electromyography or related method);
• • Pregnancy;
• • Participation in any other clinical trial;
• • Member or a family member of the personnel of the investigational or Sponsor staff directly involved with this trial.